Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16946450 | 0.91 | FURIN (0.42) | FURINKLKB1CALCRLSSTR3LTA4H | |
| SCHEMBL16645085 | 0.89 | FURIN (0.45) | FURINKLKB1CALCRLSSTR3MMP3 | |
| SCHEMBL15810600 | 0.85 | KLKB1 (0.43) | FURINKLKB1SSTR3LTA4HMMP3 | |
| SCHEMBL17752524 | 0.84 | CTSL (0.43) | FURINKLKB1CALCRLMMP3SIRT1 | |
| SCHEMBL15686242 | 0.82 | NMT2 (0.45) | FURINKLKB1CALCRLSSTR3PLG | |
| SCHEMBL25064729 | 0.82 | NPY5R (0.44) | FURINSIRT5SIRT1SIRT2SIRT3 | |
| SCHEMBL23515087 | 0.82 | SIRT2 (0.46) | FURINSIRT1SIRT2SIRT3 | |
| SCHEMBL24906651 | 0.82 | SIRT1 (0.45) | FURINKLKB1SSTR3MMP3PDF | |
| SCHEMBL24390289 | 0.82 | SIRT1 (0.45) | FURINKLKB1SSTR3MMP3PDF | |
| SCHEMBL26192867 | 0.82 | MMP3 (0.43) | FURINKLKB1CALCRLSSTR3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150104407-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150104407-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | FURIN 3298/4885KLKB1 3486/4885CALCRL 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.