Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785995 | 0.87 | L3MBTL1 (0.53) | CTSBCTSSCTSKPIN1L3MBTL1 | |
| SCHEMBL7340638 | 0.81 | CTSK (0.53) | CTSSCTSKCTSLPOLBMAPT | |
| SCHEMBL7340634 | 0.81 | CTSK (0.53) | CTSSCTSKCTSLPOLBMAPT | |
| SCHEMBL5921796 | 0.79 | GPR132 (0.59) | ROCK2POLBMAPTTDP1GAA | |
| SCHEMBL27556148 | 0.79 | PRSS1 (0.56) | CTSKPOLBMAPTTDP1RAB9A | |
| SCHEMBL27041646 | 0.78 | CTSK (0.60) | CTSBCTSSCTSKCTSLPOLB | |
| SCHEMBL27041650 | 0.78 | CTSK (0.60) | CTSBCTSSCTSKCTSLPOLB | |
| SCHEMBL30291613 | 0.77 | MMP1 (0.53) | CTSBCTSSCTSKCTSLPOLB | |
| SCHEMBL24785384 | 0.77 | PSMB5 (0.57) | L3MBTL1 | |
| SCHEMBL16576408 | 0.76 | PIN1 (0.56) | CTSBCTSSCTSKPIN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265577-A2 | CORONAVIRUS ENZYME MODULATORS, METHODS OF SYNTHESIS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-12-22 | — | — | WO | disclosed |