Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291613 | 0.81 | MMP1 (0.53) | REN | |
| SCHEMBL27041646 | 0.80 | CTSK (0.60) | REN | |
| SCHEMBL27041650 | 0.80 | CTSK (0.60) | REN | |
| SCHEMBL24832472 | 0.80 | L3MBTL1 (0.53) | PSMB5L3MBTL1USP30KMT2AMEN1 | |
| SCHEMBL10946955 | 0.78 | REN (0.57) | PSMB5ATMCACNA1BREN | |
| SCHEMBL10668564 | 0.78 | KMT2A (0.59) | PSMB5ATMKMT2AMEN1 | |
| SCHEMBL28768595 | 0.77 | CTSS (0.56) | ATMKMT2AMEN1REN | |
| SCHEMBL29651392 | 0.77 | CTSS (0.56) | ATMKMT2AMEN1REN | |
| SCHEMBL28768596 | 0.77 | CTSS (0.56) | ATMKMT2AMEN1REN | |
| SCHEMBL28269239 | 0.77 | CTSS (0.56) | ATMKMT2AMEN1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265577-A2 | CORONAVIRUS ENZYME MODULATORS, METHODS OF SYNTHESIS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-12-22 | — | — | WO | disclosed |