SCHEMBL2478499

SCHEMBL2478499

Oc1ccc(CCCCC(n2nnc3ccccc32)n2nnc3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RPS6KA3 P51812 1/20 0.43
▸ ASAH1 Q13510 1/20 0.43
▸ NPC1 O15118 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ TRPV1 Q8NER1 1/20 0.39
▸ PLA2G4A P47712 1/20 0.39
▸ PTPN2 P17706 1/20 0.38
▸ PTPN1 P18031 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ ATM Q13315 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ ESR1 P03372 2/20 0.36
▸ ADRA2A P08913 2/20 0.36
▸ ADORA3 P0DMS8 2/20 0.36
▸ TACR2 P21452 2/20 0.36
▸ SLC6A2 P23975 2/20 0.36
▸ SLC6A4 P31645 2/20 0.36
▸ SLC6A3 Q01959 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3651402 0.77 MAPT (0.61) RPS6KA3NPC1MAPTRAB9APLA2G4A
SCHEMBL1764460 0.76 MAPT (0.60) RPS6KA3NPC1MAPTRAB9APLA2G4A
SCHEMBL6037370 0.71 POLB (0.50) RPS6KA3MAPTPTPN2PTPN1POLB
SCHEMBL24503911 0.69 NPC1 (0.48) ASAH1NPC1MAPTRAB9APTPN2
SCHEMBL16398499 0.68 GRM2 (0.75) RPS6KA3NPC1MAPTRAB9ATDP1
SCHEMBL3415845 0.68 ESR1 (0.36) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL9091544 0.66 POLB (0.55) MAPTRAB9APOLBMAPK1ATM
SCHEMBL31066856 0.66 SLC9A1 (0.55) ASAH1MAPTPLA2G4APOLBMAPK1
SCHEMBL25613143 0.66 SLC9A1 (0.55) ASAH1MAPTPLA2G4APOLBMAPK1
SCHEMBL27542130 0.66 ESR1 (0.46) NPC1MAPTRAB9ATRPV1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2942047-B1 Cosmetic product BEIERSDORF AG (DE) 2020-09-02 — — EP disclosed
EP-2942045-B1 Bead-shaped cosmetic dosage forms BEIERSDORF AG (DE) 2018-10-10 — — EP disclosed
EP-2942046-B1 Compositions having an outer gel phase and an inner particulate phase, containing stabilised oxidation and/or UV-sensitive active agents BEIERSDORF AG (DE) 2018-07-11 — — EP disclosed
EP-3139897-A1 PREPARATIONS HAVING AN OUTER GEL PHASE AND AN INNER PARTICULATE PHASE COMPRISING STABILIZED OXIDATION-AND/OR UV-SENSITIVE ACTIVE INGREDIENTS Beiersdorf AG (DE) 2017-03-15 — — EP disclosed
EP-3139893-A1 COSMETIC PRODUCT Beiersdorf AG (DE) 2017-03-15 — — EP disclosed
EP-3139896-A1 BEAD-SHAPED COSMETIC DOSAGE FORMS Beiersdorf AG (DE) 2017-03-15 — — EP disclosed
US-20170050054-A1 COSMETIC PRODUCT BEIERSDORF AG (DE) 2017-02-23 — — US disclosed
WO-2015169456-A1 COSMETIC PRODUCT BEIERSDORF AG (DE) 2015-11-12 — — WO disclosed
WO-2015169455-A1 PREPARATIONS HAVING AN OUTER GEL PHASE AND AN INNER PARTICULATE PHASE COMPRISING STABILIZED OXIDATION-AND/OR UV-SENSITIVE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2015-11-12 — — WO disclosed
WO-2015169454-A1 BEAD-SHAPED COSMETIC DOSAGE FORMS BEIERSDORF AG (DE) 2015-11-12 — — WO disclosed
EP-1423083-A1 STABILISATION OF OXIDATION-SENSITIVE AND UV-SENSITIVE ACTIVE INGREDIENTS Beiersdorf AG (DE) 2004-06-02 — — EP disclosed
EP-1423088-A2 STABILISATION OF OXIDATION-SENSITIVE AND UV-SENSITIVE ACTIVE INGREDIENTS Beiersdorf AG (DE) 2004-06-02 — — EP disclosed
EP-1423087-A1 STABILISATION OF OXIDATION-SENSITIVE AND/OR UV-SENSITIVE ACTIVE INGREDIENTS Beiersdorf AG (DE) 2004-06-02 — — EP disclosed
WO-2003039506-A2 COSMETIC AND DERMATOLOGICAL LIGHT PROTECTION FORMULATIONS WITH A CONTENT OF HYDROXYBENZOPHENONES AND ALKYLNAPHTHALATES BEIERSDORF AG (DE) 2003-05-15 — — WO disclosed
WO-2003020234-A1 STABILISATION OF OXIDATION-SENSITIVE AND/OR UV-SENSITIVE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2003-03-13 — — WO disclosed
WO-2003020232-A2 STABILISATION OF COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING REPELLENT ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2003-03-13 — — WO disclosed
WO-2003020233-A2 STABILISATION OF UV-SENSITIVE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2003-03-13 — — WO disclosed
WO-2003020317-A2 COSMETIC AND DERMATOLOGICAL LIGHT-PROTECTIVE FORMULATION WITH A CONTENT OF WATER-SOLUBLE UV-FILTER SUBSTANCES AND ALKYLNAPHTHALATES BEIERSDORF AG (DE) 2003-03-13 — — WO disclosed
WO-2003020235-A2 STABILISATION OF OXIDATION-SENSITIVE AND UV-SENSITIVE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2003-03-13 — — WO disclosed
WO-2003020224-A1 STABILISATION OF OXIDATION-SENSITIVE AND UV-SENSITIVE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2003-03-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170050054-A1 COSMETIC PRODUCT POLR1C, CUTA, TNF RPS6KA3 3043/4885ASAH1 1466/4885NPC1 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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