Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21470789 | 0.77 | MGAM (0.31) | GAA | |
| SCHEMBL30614236 | 0.76 | LMNA (0.51) | ELANENUDT1KDM4EGAALMNA | |
| SCHEMBL20489068 | 0.76 | LMNA (0.51) | ELANENUDT1KDM4EGAALMNA | |
| SCHEMBL24798633 | 0.76 | KDM4E (0.38) | KDM4EGAALMNARAB9ATSHR | |
| SCHEMBL18855425 | 0.70 | GAA (0.46) | KDM4EGLAGAAALDH1A1RAB9A | |
| SCHEMBL24797980 | 0.69 | BRD4 (0.34) | GAAL3MBTL1NPSR1 | |
| SCHEMBL20439496 | 0.67 | XDH (0.31) | — | |
| SCHEMBL31347255 | 0.67 | NUDT1 (0.52) | ELANENUDT1KDM4EALDH1A1RAB9A | |
| SCHEMBL11655288 | 0.67 | KDM4E (0.59) | NUDT1KDM4EGAALMNAALDH1A1 | |
| SCHEMBL31347150 | 0.66 | NUDT1 (0.54) | ELANENUDT1KDM4ELMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589618-B1 | PYRAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2022-12-28 | — | — | EP | disclosed |