SCHEMBL2480694

SCHEMBL2480694

Cc1ccccc1C(=C(C(=O)O)C(C)C)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46
HPGD P15428 4/20 0.43
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
HTT P42858 2/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 3/20 0.40
ALOX15 P16050 1/20 0.40
POLB P06746 1/20 0.40
MYC P01106 1/20 0.40
KDM4E B2RXH2 1/20 0.39
HSD17B10 Q99714 1/20 0.39
RECQL P46063 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15913385 0.84 ERCC5 (0.47) ERCC5FEN1HPGDKMT2ACYP3A4
SCHEMBL5271348 0.81 CLCN2 (0.41) KMT2AHTTGAAALDH1A1ALOX15
SCHEMBL1173261 0.77 PGR (0.43) HPGDKMT2ACYP3A4HTTGAA
SCHEMBL4849630 0.73 LMNA (0.36) HPGDKMT2ACYP3A4SMN1; SMN2ALDH1A1
SCHEMBL585832 0.72 HPGD (0.47) ERCC5FEN1HPGDKMT2AHTT
Toluene SCHEMBL1083282 0.72 LMNA (0.50) KMT2AHTTGAASMN1; SMN2ALDH1A1
SCHEMBL166031 0.70 ERCC5 (0.57) ERCC5FEN1HPGDKMT2ACYP3A4
SCHEMBL20564513 0.70 ERCC5 (0.57) ERCC5FEN1HPGDKMT2ACYP3A4
SCHEMBL9711362 0.70 ERCC5 (0.57) ERCC5FEN1HPGDKMT2ACYP3A4
Toluic Acid SCHEMBL5082804 0.69 ALDH1A1 (0.53) ERCC5FEN1HPGDKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2874507-B1 AQUEOUS TRANSPARENT OIL-IN-WATER EMULSION COMPRISING AN EMULSIFIED CAROTENOID BASF SE (DE) 2020-12-30 EP claimed
EP-2485807-B1 SUN-CARE COMPOSITIONS ISP INVESTMENTS LLC (US) 2019-07-03 EP claimed
EP-2687103-B1 Process for manufacturing an aqueous transparent oil-in-water emulsion comprising a carotenoid and emulsion produced BASF SE (DE) 2019-05-22 EP claimed
EP-1866033-B1 SUNSCREEN AEROSOL SPRAY ENSIGN LABORATORIES PTY LTD (AU) 2017-04-19 EP claimed
EP-1595936-B1 COMPOSITION FOR EXTERNAL USE VITAMIN C60 BIORES CORP (JP) 2011-10-19 EP claimed
EP-1107728-B1 COSMETIC COMPOSITIONS FOR SOLAR PROTECTION AND USES OREAL (FR) 2004-04-28 EP claimed
EP-1002523-B1 Cosmetic sunscreening compositions OREAL (FR) 2004-03-03 EP claimed
CN-116035934-A Composition based on paecilomyces acid 欧莱雅 2023-05-02 CN disclosed
EP-2000123-B1 Stable, low viscosity cosmetic compounds containing esterquat and/or dialkylquat DEB IP LTD (GB) 2015-12-09 EP disclosed
EP-2000123-A1 Stable, low viscosity cosmetic compounds containing esterquat and/or dialkylquat Evonik Goldschmidt GmbH (DE) 2008-12-10 EP disclosed
EP-1844753-A2 Utilisation of ester quats in compositions as sand repellent substances Goldschmidt GmbH (DE) 2007-10-17 EP disclosed
WO-2003084484-A2 COMPOSITION PROVIDING UV PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2003-10-16 WO disclosed