Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24807347 | 0.85 | MLYCD (0.43) | LMNAKMT2AMEN1CA1CA2 | |
| SCHEMBL25718081 | 0.82 | LMNA (0.47) | LMNAHTTMAPTPOLBANO1 | |
| SCHEMBL8244681 | 0.73 | LMNA (0.48) | LMNAHTTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL19646301 | 0.73 | GABRA1 (0.51) | LMNA | |
| SCHEMBL157484 | 0.72 | RAPGEF4 (0.44) | MAPTPOLBKMT2AMEN1ATM | |
| SCHEMBL157483 | 0.72 | ELANE (0.35) | LMNAATM | |
| SCHEMBL8743820 | 0.70 | SLC9A1 (0.40) | LMNAHTTMAPTKMT2AMEN1 | |
| SCHEMBL2280210 | 0.70 | LMNA (0.62) | LMNAHTTMAPTKMT2AMEN1 | |
| SCHEMBL8816182 | 0.69 | VCAM1 (0.50) | LMNAMAPTPOLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8743782 | 0.69 | SLC9A1 (0.39) | LMNAHTTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271970-A1 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | Singular Genomics Systems, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |