Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530 | 0.75 | ADORA2A (0.49) | LMNAALDH1A1 | |
| SCHEMBL31538786 | 0.71 | GPR84 (0.57) | LMNAGPR84ALDH1A1 | |
| Bromide SCHEMBL31538776 | 0.70 | GPR84 (0.56) | LMNAGPR84ALDH1A1 | |
| SCHEMBL10492823 | 0.69 | LMNA (0.64) | LMNAALDH1A1 | |
| SCHEMBL26178957 | 0.64 | NR1H4 (0.45) | ATM | |
| SCHEMBL13810646 | 0.62 | PRNP (0.36) | POLB | |
| SCHEMBL9806339 | 0.62 | HDAC1 (0.50) | LMNAALDH1A1 | |
| SCHEMBL31744906 | 0.61 | GPR84 (0.49) | GPR84ALDH1A1 | |
| SCHEMBL23029792 | 0.61 | HDAC8 (0.51) | LMNAALDH1A1ATM | |
| SCHEMBL10599649 | 0.60 | KMT2A (0.58) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272307-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |