Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 5/20 | 0.39 |
| ▸ | ADH1C | P00326 | 4/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5179178 | 0.87 | SLC6A2 (0.33) | SHBGADH1AADH1CADH1BFDPS | |
| SCHEMBL896726 | 0.83 | SHBG (0.42) | SHBGADH1AADH1CADH1BMEN1 | |
| SCHEMBL737781 | 0.81 | ADH1A (0.39) | SHBGADH1AADH1CADH1BFDPS | |
| SCHEMBL17056102 | 0.79 | SHBG (0.39) | SHBGADH1AADH1CADH1BMEN1 | |
| SCHEMBL11007702 | 0.79 | ADH1A (0.38) | SHBGADH1AADH1CADH1BFDPS | |
| SCHEMBL11700387 | 0.79 | FDPS (0.42) | ADH1AADH1CADH1BFDPS | |
| SCHEMBL10448345 | 0.79 | FDPS (0.42) | ADH1AADH1CADH1BFDPS | |
| SCHEMBL17053458 | 0.79 | SHBG (0.39) | SHBGADH1AADH1CADH1BMEN1 | |
| SCHEMBL20988082 | 0.78 | SHBG (0.42) | SHBGADH1AADH1CADH1BFDPS | |
| SCHEMBL737870 | 0.78 | ADH1C (0.35) | ADH1AADH1CADH1BFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503946-B | The manufacturing method of hydroxymethyl phosphonic acid ester, polyurethane foam formation composition, polyurethane foam and the product being made from it | ICL-IP美国公司 | 2018-10-12 | — | — | CN | claimed |
| CN-105503946-A | Method for making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP America Inc | 2016-04-20 | — | — | CN | claimed |
| CN-102256987-B | Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom | ICL-IP AMERICA INC. (US) | 2016-01-13 | — | — | CN | claimed |
| US-9187504-B2 | Method of making hydroxymethylphosphonate | ICL-IP AMERICA INC. (US) | 2015-11-17 | — | — | US | claimed |
| EP-2376507-B1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATES | ICL IP AMERICA INC (US) | 2013-05-15 | — | — | EP | claimed |
| US-8198341-B2 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP AMERICA INC. (US) | 2012-06-12 | — | — | US | claimed |
| CN-102256987-A | Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom | ICL IP AMERICAN CORP | 2011-11-23 | — | — | CN | claimed |
| US-20110257287-A1 | Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom | STOWELL JEFFREY K | 2011-10-20 | — | — | US | claimed |
| US-20100160468-A1 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP AMERICA INC. | 2010-06-24 | — | — | US | claimed |
| EP-3553068-B1 | YDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL IP AMERICA INC (US) | 2021-04-28 | — | — | EP | disclosed |
| EP-3553068-A1 | HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL-IP America Inc. (US) | 2019-10-16 | — | — | EP | disclosed |
| EP-2909218-B1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL IP AMERICA INC (US) | 2019-07-10 | — | — | EP | disclosed |
| CN-105503946-B | The manufacturing method of hydroxymethyl phosphonic acid ester, polyurethane foam formation composition, polyurethane foam and the product being made from it | ICL-IP美国公司 | 2018-10-12 | — | — | CN | disclosed |
| EP-3342774-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG Chem, Ltd. (KR) | 2018-07-04 | — | — | EP | disclosed |
| US-8198341-B2 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP AMERICA INC. (US) | 2012-06-12 | — | — | US | disclosed |
| CN-102256987-A | Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom | ICL IP AMERICAN CORP | 2011-11-23 | — | — | CN | disclosed |
| US-20110257287-A1 | Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom | STOWELL JEFFREY K | 2011-10-20 | — | — | US | disclosed |
| EP-2376507-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM | ICL-IP America Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010080425-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM | SUPRESTA LLC. (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100160468-A1 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP AMERICA INC. | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257287-A1 | Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom | PFAS, PGM2, NEFM | SHBG 2239/4885ADH1A 1854/4885ADH1C 1581/4885 |
| US-20100160468-A1 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | PFAS, PGM2, NEFM | SHBG 2239/4885ADH1A 1854/4885ADH1C 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.