SCHEMBL248173

SCHEMBL248173

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC(=O)C4CCCC(O)[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1L1 Q9UHC9 5/20 0.72
USP2 O75604 4/20 0.72
LMNA P02545 3/20 0.72
FNTA P49354 4/20 0.54
FNTB P49356 4/20 0.54
CDC25A P30304 2/20 0.53
ABCB1 P08183 1/20 0.52
OSBP P22059 1/20 0.52
RORC P51449 1/20 0.52
OSBP2 Q969R2 1/20 0.52
CYP46A1 Q9Y6A2 1/20 0.52
CDC25B P30305 1/20 0.52
SRD5A1 P18405 3/20 0.52
SRD5A2 P31213 3/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
RORA P35398 1/20 0.51
ALOX15 P16050 1/20 0.51
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11321979 1.00 NPC1L1 (0.72) NPC1L1USP2LMNAFNTAFNTB
SCHEMBL1517830 0.89 NPC1L1 (0.57) NPC1L1USP2LMNAFNTAFNTB
SCHEMBL7864908 0.87 NPC1L1 (0.65) NPC1L1USP2LMNAFNTAFNTB
SCHEMBL14924215 0.85 USP2 (0.74) NPC1L1USP2LMNAFNTAFNTB
SCHEMBL863638 0.85 USP2 (0.74) NPC1L1USP2LMNAFNTAFNTB
SCHEMBL29015206 0.85 USP2 (0.74) NPC1L1USP2LMNAFNTAFNTB
SCHEMBL7990435 0.85 NPC1L1 (0.62) NPC1L1USP2LMNAFNTAFNTB
SCHEMBL11335948 0.85 NPC1L1 (0.62) NPC1L1USP2LMNAFNTAFNTB
SCHEMBL7861693 0.84 USP2 (0.61) NPC1L1USP2LMNAFNTAFNTB
5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL248174 0.84 NPC1L1 (1.00) NPC1L1USP2LMNAFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 930 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062716-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS POPVAX PRIVATE LTD (IN) 2026-03-05 US claimed
EP-4577196-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS Popvax Private Limited (IN) 2025-07-02 EP claimed
WO-2025052180-A2 LIPIDS AND LIPID NANOPARTICLES Axelyf ehf. (IS) 2025-03-13 WO claimed
WO-2024044178-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS POPVAX PRIVATE LIMITED (IN) 2024-02-29 WO claimed
EP-3368024-B1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER AKOS BIOSCIENCES INC (US) 2023-09-20 EP claimed
US-20220054429-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER AKOS BIOSCIENCES, INC. 2022-02-24 US claimed
EP-2411052-B1 CARRIER COMPRISING A VITAMIN E DERIVATIVE AND ANNEXIN V UCL BUSINESS LTD (GB) 2020-10-07 EP claimed
US-20180311182-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER AKOS BIOSCIENCES, INC. 2018-11-01 US claimed
EP-3368024-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER Jay Pharma, Inc. (CA) 2018-09-05 EP claimed
WO-2017072773-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER NATHAN ILANA (IL) 2017-05-04 WO claimed
US-9580711-B2 Lipid particles with asymmetric cationic lipids for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2017-02-28 US claimed
US-9545392-B2 Carrier comprising a vitamin E derivative UCL BUSINESS PLC (GB) 2017-01-17 US claimed
US-20160244761-A1 LIPID PARTICLES WITH ASYMMETRIC CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2016-08-25 US claimed
US-20120115771-A1 CARRIER UCL BUSINESS PLC (GB) 2012-05-10 US claimed
EP-2411052-A2 CARRIER COMPRISING A VITAMIN E DERIVATIVE UCL Business PLC (GB) 2012-02-01 EP claimed
WO-2010109212-A2 CARRIER UCL BUSINESS PLC (GB) 2010-09-30 WO claimed
JP-5221901-A None JP disclosed
US-12637422-B2 Ionizable cationic lipid for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2026-05-26 US disclosed
JP-H05221901-A SECOSTEROL DERIVATIVE SHIONO CHEM KK 1993-08-31 JP disclosed
US-RE30538-E VITAMIN D3 DERIVATIVE WHICH PROMOTES INTESTINAL CALCIUM TRANSPORT AND BONE CALCIUM MOBILIZATION WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1981-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062716-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS CETP, PLTP, LDLR NPC1L1 5/4885USP2 3448/4885LMNA 123/4885
US-12637422-B2 Ionizable cationic lipid for RNA delivery POLRMT, SLC27A1, SLC43A1 NPC1L1 6/4885USP2 4022/4885LMNA 287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.