Sugi Predict

Sugi Predict / Compounds / Triethylene Glycol

Triethylene Glycol

Triethylene Glycol

SCHEMBL2487016

CCCCCCCCOc1ccccc1.OCCOCCOCCO

nearest known ligand 0.66

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.66
▸ MEN1 O00255 2/20 0.66
▸ KMT2A Q03164 2/20 0.66
▸ LMNA P02545 2/20 0.66
▸ CYP3A4 P08684 2/20 0.66
▸ MAPK1 P28482 2/20 0.66
▸ SMN1; SMN2 Q16637 2/20 0.66
▸ USP2 O75604 1/20 0.66
▸ CASP1 P29466 1/20 0.66
▸ SLCO1B3 Q9NPD5 1/20 0.66
▸ SLCO1B1 Q9Y6L6 1/20 0.66
▸ LTA4H P09960 2/20 0.62
▸ HTT P42858 2/20 0.61
▸ THRB P10828 1/20 0.61
▸ MAPT P10636 1/20 0.61
▸ RECQL P46063 1/20 0.58
▸ NR5A1 Q13285 1/20 0.54
▸ MLNR O43193 1/20 0.54
▸ NR1I2 O75469 1/20 0.54
▸ ESR1 P03372 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL2485875 1.00 ALDH1A1 (0.66) ALDH1A1MEN1KMT2ALMNACYP3A4
Triethylene Glycol SCHEMBL2484230 1.00 ALDH1A1 (0.66) ALDH1A1MEN1KMT2ALMNACYP3A4
Tetraethylene Glycol SCHEMBL2487341 1.00 ALDH1A1 (0.66) ALDH1A1MEN1KMT2ALMNACYP3A4
Hexaethylene Glycol SCHEMBL11084821 1.00 ALDH1A1 (0.66) ALDH1A1MEN1KMT2ALMNACYP3A4
Di(Hydroxyethyl)Ether SCHEMBL2485682 0.98 LTA4H (0.64) ALDH1A1MEN1KMT2ALMNACYP3A4
Di(Hydroxyethyl)Ether SCHEMBL2482141 0.98 LTA4H (0.64) ALDH1A1MEN1KMT2ALMNACYP3A4
SCHEMBL7913444 0.97 ALDH1A1 (0.67) ALDH1A1MEN1KMT2ALMNACYP3A4
SCHEMBL28323872 0.97 LTA4H (0.62) ALDH1A1MEN1KMT2ALMNACYP3A4
Ethylene Glycol SCHEMBL28314132 0.95 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ALMNACYP3A4
Phenoxyethanol SCHEMBL2501075 0.95 ALDH1A1 (0.61) ALDH1A1MEN1KMT2ALMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110072856-B Process for producing alpha-hydroxycarboxylic acid dimer cyclic ester 株式会社吴羽 2022-03-15 — — CN disclosed
CN-111699179-B Method for producing cyclic ester 株式会社吴羽 2021-09-17 — — CN disclosed
CN-111741953-B Method for producing glycolide 株式会社吴羽 2021-05-28 — — CN disclosed
CN-111757873-A Method for producing glycolide 株式会社吴羽 2020-10-09 — — CN disclosed
CN-111741952-A Method for producing glycolide 株式会社吴羽 2020-10-02 — — CN disclosed
CN-111741953-A Method for producing glycolide 株式会社吴羽 2020-10-02 — — CN disclosed
CN-111699179-A Method for producing cyclic ester 株式会社吴羽 2020-09-22 — — CN disclosed
WO-2019181516-A1 GLYCOLIDE PRODUCTION METHOD 株式会社クレハ 2019-09-26 — — WO disclosed
WO-2019181298-A1 METHOD FOR PRODUCING GLYCOLIDE 株式会社クレハ 2019-09-26 — — WO disclosed
WO-2019181340-A1 GLYCOLIDE PRODUCTION METHOD 株式会社クレハ 2019-09-26 — — WO disclosed
EP-2377858-B1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORP (JP) 2014-04-30 — — EP disclosed
US-20120289713-A1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORPORATION (JP) 2012-11-15 — — US disclosed
US-20110263875-A1 Production Process of Glycolide KUREHA CORPORATION (JP) 2011-10-27 — — US disclosed
EP-2377858-A1 METHOD FOR PRODUCING GLYCOLIDE Kureha Corporation (JP) 2011-10-19 — — EP disclosed
US-7812181-B2 Process for producing glycolide and glycolic acid oligomer for production of glycolide KUREHA CORPORATION (JP) 2010-10-12 — — US disclosed
US-20070293653-A1 depolymerizing polyglycolic acid by heating in an organic solvent; system is controlled to suppress efffective concentration of impurities (ammonia, amines or amides, methoxyacetic acid and diglycolic acid); high purity glycolide starting material for polyglycolic acid KUREHA CORPORATION (JP) 2007-12-20 — — US disclosed
EP-1310496-B1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA CORP (JP) 2006-12-06 — — EP disclosed
US-6916939-B2 Process for the preparation of cyclic esters and method for purification of the same KUREHA KAGAKU KOGYO K.K. (JP) 2005-07-12 — — US disclosed
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same KUREHA CORPORATION (JP) 2003-10-09 — — US disclosed
EP-1310496-A1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-05-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same CEL, CETP, MCCC2 ALDH1A1 2201/4885MEN1 3285/4885KMT2A 3678/4885
US-20110263875-A1 Production Process of Glycolide RPN2, RPN1, DDOST ALDH1A1 2965/4885MEN1 4593/4885KMT2A 4858/4885
US-20120289713-A1 METHOD FOR PRODUCING GLYCOLIDE DDOST, MAGT1, UGCG ALDH1A1 4614/4885MEN1 2615/4885KMT2A 4626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.