Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | KYNU | Q16719 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL4728793 | 1.00 | OTC (0.40) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL5606089 | 0.88 | ALDH1A1 (0.45) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL4208935 | 0.88 | ALDH1A1 (0.45) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL28111285 | 0.85 | OTC (0.39) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL12006798 | 0.84 | OTC (0.43) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL1287134 | 0.84 | OTC (0.43) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL8525152 | 0.84 | ALDH1A1 (0.41) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL28268971 | 0.84 | OTC (0.53) | OTCKMT2ADDAH1 | |
| Arginine SCHEMBL28911625 | 0.83 | OTC (0.43) | OTCPOLBKMT2ATDP1DDAH1 | |
| Arginine SCHEMBL26914670 | 0.83 | KIF11 (0.46) | OTCPOLBKMT2ATDP1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11633452-B2 | Compositions and methods for treating vaginal dryness | THE PROCTER & GAMBLE COMPANY (US) | 2023-04-25 | — | — | US | claimed |
| EP-3787656-A1 | COMPOSITIONS AND METHODS FOR TREATING VAGINAL DRYNESS | The Procter & Gamble Company (US) | 2021-03-10 | — | — | EP | claimed |
| US-20210038679-A1 | COMPOSITIONS AND METHODS FOR TREATING VAGINAL DRYNESS | THE PROCTER & GAMBLE COMPANY | 2021-02-11 | — | — | US | claimed |
| CN-112088010-A | Compositions and methods for treating vaginal dryness | 宝洁公司 | 2020-12-15 | — | — | CN | claimed |
| US-20170304187-A1 | EMU Oil In Combination With Other Active Ingredients For Treating Skin Imperfections | DESAI, KETAN | 2017-10-26 | — | — | US | claimed |
| US-11633452-B2 | Compositions and methods for treating vaginal dryness | THE PROCTER & GAMBLE COMPANY (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220409518-A1 | EMU Oil In Combination With Other Active Ingredients For Treating Skin Imperfections | DESAI, KETAN | 2022-12-29 | — | — | US | disclosed |
| EP-3787656-A1 | COMPOSITIONS AND METHODS FOR TREATING VAGINAL DRYNESS | The Procter & Gamble Company (US) | 2021-03-10 | — | — | EP | disclosed |
| US-20210038679-A1 | COMPOSITIONS AND METHODS FOR TREATING VAGINAL DRYNESS | THE PROCTER & GAMBLE COMPANY | 2021-02-11 | — | — | US | disclosed |
| CN-112088010-A | Compositions and methods for treating vaginal dryness | 宝洁公司 | 2020-12-15 | — | — | CN | disclosed |
| EP-3366274-A1 | COSMETIC BIOPHOTONIC COMPOSITIONS | KLOX Technologies, Inc. (CA) | 2018-08-29 | — | — | EP | disclosed |
| US-20170326378-A1 | COSMETIC BIOPHOTONIC COMPOSITIONS | KLOX TECHNOLOGIES INC. (CA) | 2017-11-16 | — | — | US | disclosed |
| WO-2001001933-A2 | PRE-FORMED, SELF-ADHESIVE SHEET DEVICES SUITABLE FOR TOPICAL APPLICATION | THE PROCTER & GAMBLE COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2001001951-A1 | SHEET-LIKE DEVICES | THE PROCTER & GAMBLE COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2001002028-A2 | PRE-FORMED, SHEET DEVICES SUITABLE FOR TOPICAL APPLICATION | THE PROCTER & GAMBLE COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2001002477-A1 | PRE-FORMED, SELF-ADHESIVE SHEETS SUITABLE FOR TOPICAL APPLICATION | THE PROCTER & GAMBLE COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2001001952-A1 | DEVICES | THE PROCTER & GAMBLE COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2001001816-A1 | COSMETIC OR DERMAPHARMACEUTICAL PATCH | PROCTER & GAMBLE COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| US-5734080-A | SKIN DISORDERS; WOUND HEALING AGENT | ANIHEALTH CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |
| WO-1997010830-A1 | REACTION PRODUCT OF ARGININE AND p-AMINOBENZOIC ACID | SCHUTT STEVEN R (US) | 1997-03-27 | — | — | WO | disclosed |