Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | IL4I1 | Q96RQ9 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | APLNR | P35414 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851921 | 0.78 | GUSB (0.54) | IDH1IL4I1KDM4E | |
| SCHEMBL24851962 | 0.77 | IL4I1 (0.51) | PDE10ASMN1; SMN2ALDH1A1IL4I1TSHR | |
| SCHEMBL24852507 | 0.75 | IL4I1 (0.51) | PDE10ANPSR1SMN1; SMN2ALDH1A1IL4I1 | |
| SCHEMBL24852046 | 0.73 | KDM4E (0.46) | PDE10ANPSR1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL24852000 | 0.73 | EGFR (0.55) | SMN1; SMN2ALDH1A1IL4I1TSHRMAPT | |
| SCHEMBL24852008 | 0.73 | GUSB (0.51) | PDE10ANPSR1ALDH1A1IL4I1KDM4E | |
| SCHEMBL3717832 | 0.72 | IL4I1 (0.66) | IDH1NPSR1SMN1; SMN2ALDH1A1IL4I1 | |
| SCHEMBL24851917 | 0.72 | IL4I1 (0.42) | IDH1PDE10ANPSR1ALDH1A1IL4I1 | |
| SCHEMBL24852035 | 0.72 | ALDH1A1 (0.56) | IDH1PDE10ANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24851920 | 0.71 | IL4I1 (0.47) | NPSR1TP53ALDH1A1IL4I1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278222-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2023-01-05 | — | — | WO | disclosed |