Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483018 | 0.89 | CYP1A2 (0.46) | CTSSCTSKBTKGAAHDAC4 | |
| SCHEMBL4291920 | 0.88 | CTSS (0.48) | CTSSCTSKBTKGAAHDAC4 | |
| SCHEMBL9358337 | 0.81 | KMT2A (0.49) | CTSSCTSKBTKGAAHDAC4 | |
| SCHEMBL9358329 | 0.81 | KMT2A (0.49) | CTSSCTSKBTKGAAHDAC4 | |
| SCHEMBL6924668 | 0.80 | BTK (0.43) | CTSSCTSKBTKGAAHDAC4 | |
| SCHEMBL20470214 | 0.80 | KMT2A (0.50) | CTSSCTSKBTKGAAHDAC4 | |
| SCHEMBL22506480 | 0.80 | KMT2A (0.50) | CTSSCTSKBTKGAAHDAC4 | |
| SCHEMBL20470278 | 0.80 | KMT2A (0.50) | CTSSCTSKBTKGAAHDAC4 | |
| SCHEMBL2714461 | 0.79 | CTSK (0.49) | CTSSCTSKBTKHDAC4HDAC1 | |
| SCHEMBL6759376 | 0.79 | CTSK (0.47) | CTSSCTSKBTKGAAHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304216-B2 | Method for production of erythro-or threo-2-amino-3-hydroxypropionic acid ester, novel carbonyl reductase, gene for the reductase, vector, transformant, and method for production of optically active alcohol using those | KANEKA CORPORATION (JP) | 2012-11-06 | — | — | US | disclosed |
| EP-1995314-B1 | METHOD FOR PRODUCTION OF ERYTHRO- OR THREO-2-AMINO-3-HYDROXYPROPIONIC ACID ESTER, NOVEL CARBONYL REDUCTASE, GENE FOR THE REDUCTASE, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOL USING THOSE | KANEKA CORP (JP) | 2011-10-19 | — | — | EP | disclosed |
| US-20090186391-A1 | Method for Production of Erythro-or threo-2-Amino-3-Hydroxypropionic Acid Ester, Novel Carbonyl Reductase, Gene for the Reductase, Vector, Transformant, and Method for Production of Optically Active Alcohol Using Those | KANEKA CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1995314-A1 | METHOD FOR PRODUCTION OF ERYTHRO- OR THREO-2-AMINO-3-HYDROXYPROPIONIC ACID ESTER, NOVEL CARBONYL REDUCTASE, GENE FOR THE REDUCTASE, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOL USING THOSE | Kaneka Corporation (JP) | 2008-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186391-A1 | Method for Production of Erythro-or threo-2-Amino-3-Hydroxypropionic Acid Ester, Novel Carbonyl Reductase, Gene for the Reductase, Vector, Transformant, and Method for Production of Optically Active Alcohol Using Those | ADH5, ADH1C, ADH1A | CTSS 4782/4885CTSK 4790/4885BTK 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.