Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | Q9HBH1 | 1/20 | 0.38 | |
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 4/20 | 0.37 |
| ▸ | NMT1 | P30419 | 4/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16645085 | 0.88 | FURIN (0.45) | FURINKLKB1PDFCALCRLNMT2 | |
| SCHEMBL19508510 | 0.86 | FURIN (0.39) | FURINHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15686242 | 0.86 | NMT2 (0.45) | FURINHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL24864487 | 0.81 | KLKB1 (0.44) | FURINITGB1KLKB1PDFCALCRL | |
| SCHEMBL20332469 | 0.81 | CA2 (0.45) | FURINHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29335395 | 0.81 | KLKB1 (0.43) | FURINKLKB1PDFCALCRLPLG | |
| SCHEMBL29342074 | 0.80 | KLKB1 (0.42) | FURINKLKB1PDFCALCRLNMT2 | |
| SCHEMBL24864663 | 0.79 | KLKB1 (0.48) | KLKB1PDFCALCRLNMT2NMT1 | |
| SCHEMBL18738463 | 0.79 | SMN1; SMN2 (0.45) | KLKB1PDFCALCRLNMT2NMT1 | |
| SCHEMBL14978855 | 0.78 | NMT2 (0.45) | FURINKLKB1CALCRLNMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016054315-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | MEDIMMUNE, LLC (US) | 2016-04-07 | — | — | WO | disclosed |