Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865690 | 0.84 | OPRK1 (0.35) | OPRK1OPRM1GAAALDH1A1MAPT | |
| SCHEMBL24865805 | 0.81 | NOTUM (0.37) | MAPTNOTUMMAP4K1HRH3NPSR1 | |
| SCHEMBL24865618 | 0.78 | CNR2 (0.36) | GAAALDH1A1MAPTSMN1; SMN2SYK | |
| SCHEMBL30885112 | 0.78 | CNR2 (0.36) | GAAALDH1A1MAPTSMN1; SMN2SYK | |
| SCHEMBL24865745 | 0.76 | MAPK10 (0.44) | — | |
| SCHEMBL25041475 | 0.76 | GAA (0.43) | OPRK1GAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24865544 | 0.76 | BCL6 (0.35) | MAPTSMN1; SMN2CNR2HRH3 | |
| SCHEMBL24865620 | 0.76 | DRD2 (0.38) | ALDH1A1MAPTSMN1; SMN2CNR2MEN1 | |
| SCHEMBL30336093 | 0.76 | DRD2 (0.38) | ALDH1A1MAPTSMN1; SMN2CNR2MEN1 | |
| SCHEMBL24865741 | 0.76 | CNR2 (0.34) | MAPTSMN1; SMN2CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |