Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.43 |
| ▸ | SYK | P43405 | 7/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24866869 | 0.85 | PDE4A (0.42) | ACACB | |
| SCHEMBL24867489 | 0.82 | CDK2 (0.38) | ACACBSYK | |
| SCHEMBL24866872 | 0.82 | PTGS1 (0.45) | ACACBAURKAAURKBPTGS1 | |
| SCHEMBL24866886 | 0.81 | HDAC3 (0.41) | ACACB | |
| SCHEMBL24866925 | 0.80 | VNN1 (0.46) | ACACBAURKA | |
| SCHEMBL24866928 | 0.80 | VNN1 (0.46) | ACACB | |
| SCHEMBL24867208 | 0.79 | HDAC3 (0.41) | ACACB | |
| SCHEMBL24867486 | 0.78 | RAB9A (0.44) | ACACB | |
| SCHEMBL24866927 | 0.77 | AURKA (0.38) | ACACBAURKA | |
| SCHEMBL24866939 | 0.77 | VNN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |