Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867211 | 0.85 | SCN9A (0.45) | ACACBNPY5RSCN9A | |
| SCHEMBL24867283 | 0.83 | AKT1 (0.40) | — | |
| SCHEMBL24867284 | 0.81 | WNT3A (0.43) | — | |
| SCHEMBL24867286 | 0.79 | SCN9A (0.55) | SCN9A | |
| SCHEMBL24867491 | 0.76 | GRM5 (0.43) | — | |
| SCHEMBL24867289 | 0.73 | GPR55 (0.50) | — | |
| SCHEMBL24867309 | 0.71 | ACACB (0.44) | ACACB | |
| SCHEMBL24867308 | 0.71 | PRKAA2 (0.42) | ACACB | |
| SCHEMBL4575613 | 0.71 | SLC6A4 (0.48) | — | |
| SCHEMBL24867214 | 0.70 | RAB9A (0.43) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |