Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.36 |
| ▸ | CCR9 | P51686 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414232 | 0.87 | CCR9 (0.39) | FFAR4ABCB1CCR9IRAK4NTRK1 | |
| SCHEMBL3467553 | 0.81 | KDM4E (0.41) | FFAR4ABCB1NPY5R | |
| SCHEMBL27844158 | 0.74 | NPY5R (0.45) | FFAR4ABCB1CCR9NPY5R | |
| SCHEMBL7367610 | 0.72 | FFAR4 (0.41) | FFAR4ABCB1CCR9IRAK4NPY5R | |
| SCHEMBL1876083 | 0.70 | PIK3CD (0.44) | FFAR4CCR9NR1H2IRAK4HTR6 | |
| SCHEMBL1435781 | 0.66 | NPY5R (0.42) | ABCB1IRAK4NPY5RDRD2 | |
| SCHEMBL2951656 | 0.66 | DRD2 (0.40) | FFAR4ABCB1NPY5RHTR6DRD2 | |
| SCHEMBL1435785 | 0.66 | NPY5R (0.42) | ABCB1IRAK4NPY5RDRD2 | |
| SCHEMBL3709688 | 0.66 | CDC7 (0.43) | FFAR4NPY5RHTR6 | |
| SCHEMBL9009161 | 0.65 | MTNR1A (0.47) | NPY5RDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376484-A1 | OXADIAZOLE FUSED HETEROCYCLIC DERIVATIVES USEFUL FOR THE TREATMENT OF MULTIPLE SCLEROSIS | Merck Serono S.A. (CH) | 2011-10-19 | — | — | EP | disclosed |