Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27844158 | 0.88 | NPY5R (0.45) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL3465527 | 0.84 | KMT2A (0.55) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL2487330 | 0.81 | FFAR4 (0.36) | NPY5RFFAR4ABCB1 | |
| SCHEMBL8029435 | 0.77 | ATM (0.53) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL2470686 | 0.75 | MAPT (0.48) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL9009161 | 0.74 | MTNR1A (0.47) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL14632407 | 0.74 | ALDH1A1 (0.65) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL1435781 | 0.72 | NPY5R (0.42) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL1435785 | 0.72 | NPY5R (0.42) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL2951656 | 0.72 | DRD2 (0.40) | KDM4EALDH1A1TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069949-A1 | OXADIAZOLE FUSED HETEROCYCLIC DERIVATIVES USEFUL FOR THE TREATMENT OF MULTIPLE SCLEROSIS | MERCK SERONO S.A. (CH) | 2010-06-24 | — | — | WO | disclosed |