SCHEMBL24880483

SCHEMBL24880483

CCOC(=O)c1ccc(C2=CCNCC2)nn1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CDK9 P50750 3/20 0.40
▸ CCNT1 O60563 2/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ WNT3A P56704 1/20 0.38
▸ QDPR P09417 3/20 0.37
▸ SLC6A2 P23975 3/20 0.36
▸ SLC6A4 P31645 3/20 0.36
▸ SLC6A3 Q01959 3/20 0.36
▸ SIGMAR1 Q99720 2/20 0.36
▸ SCN9A Q15858 1/20 0.35
▸ HTR2C P28335 2/20 0.35
▸ MAPT P10636 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13944380 0.76 QDPR (0.51) CYP1A2QDPRSLC6A2SLC6A4SLC6A3
SCHEMBL5642066 0.75 CYP1A2 (0.64) CYP1A2MAPTALDH1A1KDM4ELMNA
SCHEMBL12537954 0.75 NLRP3 (0.42) CDK9CCNT1CYP1A2QDPRSLC6A2
Hydrochloric Acid SCHEMBL4185793 0.75 QDPR (0.50) CYP1A2QDPRSLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL2584674 0.74 RAB9A (0.50) CYP1A2MAPTALDH1A1KDM4E
SCHEMBL23294580 0.73 AURKA (0.38) CDK9CCNT1CYP1A2QDPRSLC6A2
SCHEMBL24880775 0.73 LMNA (0.47) CDK9CCNT1QDPRSLC6A2SLC6A4
SCHEMBL4869840 0.73 TSHR (0.56) CYP1A2SLC6A2SLC6A4SLC6A3MAPT
SCHEMBL30831836 0.71 CYP1A2 (0.51) CYP1A2MAPTALDH1A1KDM4ELMNA
SCHEMBL23015245 0.70 CASP1 (0.59) CYP1A2MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383908-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER HINOVA PHARMACEUTICALS INC. (CN) 2024-11-21 — — US disclosed
CN-115594666-B Synthesis and application of phosphatase degradation agent 海创药业股份有限公司 2024-05-31 — — CN disclosed
EP-4368614-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER Hinova Pharmaceuticals Inc. (CN) 2024-05-15 — — EP disclosed
CN-115594666-A Synthesis and application of phosphatase degrading agent 海创药业股份有限公司(CN) 2023-01-13 — — CN disclosed
WO-2023280237-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER 海创药业股份有限公司 2023-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383908-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER DUSP1, PPM1D, PTPN1 CDK9 1501/4885CCNT1 1430/4885CYP1A2 1700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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