Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447393 | 0.77 | PNMT (0.54) | OPRK1OPRM1ALDH1A1 | |
| SCHEMBL18808437 | 0.76 | SIGMAR1 (0.37) | OPRD1SIGMAR1OPRK1OPRM1 | |
| SCHEMBL25305560 | 0.71 | OPRK1 (0.42) | OPRD1SIGMAR1OPRK1OPRM1 | |
| SCHEMBL9137028 | 0.70 | ALOX5 (0.44) | OPRD1SIGMAR1OPRK1OPRM1CA12 | |
| SCHEMBL18808716 | 0.67 | OPRD1 (0.37) | OPRD1SIGMAR1OPRK1OPRM1 | |
| SCHEMBL22348649 | 0.67 | PNMT (0.32) | — | |
| SCHEMBL27430682 | 0.67 | OPRD1 (0.46) | OPRD1OPRK1OPRM1CA12ALDH1A1 | |
| SCHEMBL20743911 | 0.67 | PNMT (0.45) | OPRK1OPRM1ALDH1A1LMNA | |
| SCHEMBL22347234 | 0.67 | UHRF1 (0.37) | — | |
| SCHEMBL30503536 | 0.67 | OPRM1 (0.43) | OPRD1SIGMAR1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |