Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306152 | 0.87 | CA1 (0.38) | TRPA1TRPM8 | |
| SCHEMBL29130690 | 0.77 | MGAM (0.41) | MGAMGAASIMGAM2 | |
| SCHEMBL12166532 | 0.74 | TRPA1 (0.36) | TRPA1TRPM8 | |
| SCHEMBL15982396 | 0.73 | TRPA1 (0.34) | TRPA1TRPM8MGAMGAASI | |
| SCHEMBL19176471 | 0.72 | TRPA1 (0.36) | TRPA1TRPM8 | |
| SCHEMBL4933123 | 0.72 | TRPA1 (0.39) | TRPA1TRPM8 | |
| SCHEMBL17511682 | 0.72 | TRPA1 (0.39) | TRPA1TRPM8 | |
| SCHEMBL3479985 | 0.72 | GBA1 (0.38) | — | |
| SCHEMBL27423946 | 0.71 | SI (0.34) | TRPA1TRPM8MGAMGAASI | |
| SCHEMBL12166853 | 0.71 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230020161-A1 | Tricyclic Modulators of PP2A | RAPPTA THERAPEUTICS OY (FI) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230020161-A1 | Tricyclic Modulators of PP2A | PPP2CA, PPP4C, PPP3R1 | TRPA1 3627/4885TRPM8 4546/4885MGAM 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.