Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6008290 | 0.77 | EP300 (0.36) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9147492 | 0.73 | S100B (0.33) | ALDH1A1CYP3A4TDP1 | |
| SCHEMBL15389999 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL27705827 | 0.72 | ALDH1A3 (0.33) | ALDH1A1 | |
| SCHEMBL9311864 | 0.72 | GAA (0.33) | GAA | |
| SCHEMBL27813748 | 0.72 | CCR5 (0.33) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL387883 | 0.70 | ALDH1A1 (0.42) | ALDH1A1CYP3A4KDM4EMAPTMEN1 | |
| SCHEMBL10333062 | 0.70 | ALDH1A1 (0.42) | ALDH1A1CYP3A4KDM4EMAPTMEN1 | |
| SCHEMBL7822601 | 0.69 | PRKCI (0.53) | ALDH1A1CYP3A4KDM4EMAPTMEN1 | |
| SCHEMBL27686773 | 0.69 | ALDH1A1 (0.31) | ALDH1A1CYP3A4MAPTTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379505-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | Designmedix, Inc. (US) | 2011-10-26 | — | — | EP | claimed |
| US-20110251210-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | PORTLAND STATE UNIVERSITY (US) | 2011-10-13 | — | — | US | claimed |
| WO-2010065932-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | DESIGNMEDIX, INC. (US) | 2010-06-10 | — | — | WO | claimed |
| CN-112867751-B | Dispersants for coating systems | 巴斯夫欧洲公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20210230362-A1 | A DISPERSANT FOR COATING SYSTEM | BASF SE (DE) | 2021-07-29 | — | — | US | disclosed |
| CN-112867751-A | Dispersants for coating systems | 巴斯夫欧洲公司 | 2021-05-28 | — | — | CN | disclosed |
| US-8658648-B2 | Modified chloroquines with single ring moiety or fused ring moiety | DESIGNMEDIX, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| EP-2379505-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | Designmedix, Inc. (US) | 2011-10-26 | — | — | EP | disclosed |
| US-20110251210-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | PORTLAND STATE UNIVERSITY (US) | 2011-10-13 | — | — | US | disclosed |
| WO-2010065932-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | DESIGNMEDIX, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251210-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | QARS1, MAVS, QDPR | ALDH1A1 3151/4885CYP3A4 795/4885KDM4E 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.