SCHEMBL2490789

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2491597	0.90	CHRM2 (0.40)	ALDH1A1TSHRTDP1SLC6A4SLC6A2
	SCHEMBL2489521	0.82	ALDH1A1 (0.45)	ALDH1A1TSHRTDP1KDM4EHSD17B10
	SCHEMBL2492358	0.81	ALDH1A1 (0.43)	ALDH1A1TSHRTDP1KDM4EHSD17B10
	SCHEMBL2488564	0.78	ADRB1 (0.55)	TSHRSLC6A4SLC6A2SIGMAR1ADRB1
	SCHEMBL2494066	0.74	HTR3A (0.54)	SLC6A4SLC6A2SLC6A3SIGMAR1ADRB1
	SCHEMBL569963	0.72	SIGMAR1 (0.48)	ALDH1A1TSHRSIGMAR1ADRB1HTR3E
	SCHEMBL2492127	0.71	CYP2B6 (0.49)	ALDH1A1TSHRTDP1SIGMAR1KDM4E
	SCHEMBL9090858	0.71	SIGMAR1 (0.47)	ALDH1A1TSHRSIGMAR1ADRB1HTR3E
	SCHEMBL8411629	0.71	SIGMAR1 (0.47)	ALDH1A1TSHRSIGMAR1ADRB1HTR3E
	SCHEMBL2490791	0.69	HTR5A (0.39)	ALDH1A1TSHRSLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.