SCHEMBL24909497

SCHEMBL24909497

CCC(C)(C)C(=O)CNC(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.39
RIPK1 Q13546 3/20 0.33
TET2 Q6N021 1/20 0.33
RECQL P46063 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FKBP1A P62942 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13309270 0.80 EPHX1 (0.39) EPHX1TET2RECQLALDH1A1HSD17B10
SCHEMBL12128670 0.78 KDM4E (0.36) RIPK1ALDH1A1TSHR
SCHEMBL19334206 0.78 EPHX1 (0.53) EPHX1TSHR
SCHEMBL24492714 0.75 RIPK1 (0.37) RIPK1
SCHEMBL16091819 0.73 CA1 (0.33) RIPK1RECQL
SCHEMBL9632175 0.72 TET2 (0.58) EPHX1TET2RECQLALDH1A1HSD17B10
SCHEMBL20987889 0.72 ALDH1A1 (0.45) RIPK1ALDH1A1TSHR
SCHEMBL8009840 0.71 RIPK1 (0.38) EPHX1RIPK1ALDH1A1FKBP1ATSHR
SCHEMBL12467629 0.71 DPP4 (0.34) RIPK1
SCHEMBL1230604 0.71 MGAM (0.44) RIPK1TET2RECQLALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230025932-A1 NOVEL FUNCTIONALIZED LACTONES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE PRAEVENTIX, LLC 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230025932-A1 NOVEL FUNCTIONALIZED LACTONES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE HTR7, HTR2C, HTR3A EPHX1 1401/4885RIPK1 2293/4885TET2 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.