SCHEMBL24909792

SCHEMBL24909792

N#Cc1cc(-c2cncc(C(F)(F)F)c2)c(O)c(C(F)(F)F)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 4/20 0.45
CYP11B1 P15538 3/20 0.45
CYP1A2 P05177 1/20 0.43
METAP2 P50579 1/20 0.43
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
CYP3A4 P08684 2/20 0.36
CYP3A5 P20815 2/20 0.36
RXRA P19793 1/20 0.34
RXRG P48443 1/20 0.34
KIF11 P52732 2/20 0.34
XDH P47989 2/20 0.33
SLC22A12 Q96S37 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.32
AR P10275 2/20 0.32
ERN1 O75460 2/20 0.32
PGR P06401 1/20 0.32
GYS1 P13807 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909874 0.85 MEN1 (0.46) CYP11B2CYP11B1CYP1A2METAP2PARP10
SCHEMBL24909762 0.83 RXRA (0.46) CYP1A2METAP2RXRARXRGKIF11
SCHEMBL24909776 0.82 CYP1A2 (0.40) CYP11B2CYP11B1CYP1A2METAP2XDH
SCHEMBL24909890 0.82 CYP11B1 (0.47) CYP11B2CYP11B1CYP1A2METAP2CYP3A4
SCHEMBL24909746 0.78 GYS1 (0.35) CYP11B2KIF11XDHSLC22A12AR
SCHEMBL24909893 0.77 KIF11 (0.40) CYP11B2CYP11B1CYP3A4CYP3A5KIF11
SCHEMBL24909915 0.77 KIF11 (0.41) KIF11XDHSLC22A12ARPGR
SCHEMBL24909935 0.77 KIF11 (0.36) CYP11B2KIF11XDHSLC22A12AR
SCHEMBL24910014 0.76 KIF11 (0.38) KIF11XDHSLC22A12ARPGR
SCHEMBL24909774 0.76 KIF11 (0.40) KIF11XDHSLC22A12ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 CYP11B2 644/4885CYP11B1 447/4885CYP1A2 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.