SCHEMBL24909804

SCHEMBL24909804

N#Cc1cc(-c2nc(C(F)(F)F)cs2)c(O)c(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 4/20 0.40
NTSR1 P30989 1/20 0.33
VCP P55072 1/20 0.33
PLAT P00750 1/20 0.32
PTGES O14684 1/20 0.32
TRPV4 Q9HBA0 1/20 0.31
XDH P47989 1/20 0.31
SLC22A12 Q96S37 1/20 0.31
P4HB P07237 1/20 0.30
TTR P02766 2/20 0.30
ALB P02768 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ALPL P05186 1/20 0.30
ALPI P09923 1/20 0.30
CYP19A1 P11511 1/20 0.30
AR P10275 3/20 0.30
KIF11 P52732 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31097123 0.78 CRHR1 (0.41) TRPV4XDHSLC22A12CYP19A1AR
SCHEMBL23621186 0.78 CRHR1 (0.41) TRPV4XDHSLC22A12CYP19A1AR
SCHEMBL24909927 0.77 VCP (0.39) IDH1NTSR1VCPTRPV4XDH
SCHEMBL24909405 0.77 XDH (0.34) TRPV4XDHSLC22A12P4HBTTR
SCHEMBL24909806 0.76 TRPV4 (0.33) NTSR1VCPTRPV4XDHSLC22A12
SCHEMBL24910097 0.75 PARP15 (0.39) TRPV4XDHSLC22A12ARKIF11
SCHEMBL24909418 0.74 PDE3B (0.34) TRPV4XDHSLC22A12P4HBTTR
SCHEMBL24910014 0.73 KIF11 (0.38) TRPV4XDHSLC22A12P4HBTTR
SCHEMBL24909781 0.73 PDE3B (0.37) TRPV4XDHSLC22A12P4HBTTR
SCHEMBL24910087 0.73 TRPV4 (0.34) TRPV4XDHSLC22A12P4HBTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 IDH1 36/4885NTSR1 1882/4885VCP 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.