SCHEMBL24910099

SCHEMBL24910099

CC(C)c1ccc(C(F)(F)F)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.37
PDE2A O00408 1/20 0.37
AR P10275 1/20 0.36
TRPA1 O75762 1/20 0.36
FFAR1 O14842 1/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
KIF11 P52732 1/20 0.34
NOTUM Q6P988 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
BACE1 P56817 1/20 0.33
S1PR1 P21453 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
KCNJ11 Q14654 1/20 0.32
HDAC3 O15379 1/20 0.31
CYP2C9 P11712 1/20 0.31
HDAC1 Q13547 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16849211 0.83 HSD11B1 (0.33) GABRA1GABRB2KCNJ11SMN1; SMN2
SCHEMBL17298377 0.82 KCNJ11 (0.50) KCNJ11SMN1; SMN2
SCHEMBL8781825 0.80 GABRA1 (0.48) TRPA1FFAR1GABRA1GABRB2KIF11
SCHEMBL30876294 0.80 GABRA1 (0.48) TRPA1FFAR1GABRA1GABRB2KIF11
SCHEMBL21028107 0.78 CYP3A4 (0.46) TRPA1GABRA1GABRB2KCNJ11
SCHEMBL22810212 0.78 P2RX7 (0.40) P2RX7ARTRPA1KIF11NR1H2
SCHEMBL24910166 0.77 SLC40A1 (0.44) NR1H2NR1H3TLR7
SCHEMBL15165095 0.75 SLC40A1 (0.46) NR1H2NR1H3
SCHEMBL20931032 0.74 PDE2A (0.35) PDE2A
SCHEMBL9861337 0.74 KDM4E (0.44) P2RX7ARTRPA1KIF11NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122934-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-01-25 EP disclosed