Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154504 | 0.82 | KMT2A (0.47) | LOXL2CYP2A6KMT2AKDM4ETDP1 | |
| SCHEMBL249189 | 0.80 | LOXL2 (0.58) | LOXL2CYP2A6CA12CA2CA9 | |
| SCHEMBL16216302 | 0.74 | MMP2 (0.42) | LOXL2CYP2A6KMT2AKDM4EL3MBTL1 | |
| SCHEMBL4432425 | 0.74 | ENPP2 (0.50) | KMT2AKDM4ETDP1CA12CA1 | |
| SCHEMBL23137321 | 0.74 | MMP3 (0.50) | KMT2AKDM4ETDP1L3MBTL1ENPP2 | |
| SCHEMBL5179689 | 0.74 | HDAC8 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL196175 | 0.74 | MMP3 (0.50) | KMT2AKDM4ETDP1L3MBTL1ENPP2 | |
| SCHEMBL8763328 | 0.74 | KMT2A (0.42) | LOXL2KMT2AKDM4ETDP1L3MBTL1 | |
| SCHEMBL3840593 | 0.74 | HDAC8 (0.43) | LOXL2CYP2A6HDAC8TDP1CA12 | |
| SCHEMBL10191895 | 0.73 | CYP1A1 (0.43) | LOXL2CYP2A6KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459508-A | Iridium complex for inducing Mutp to degrade and preparation method and application thereof | 南京师范大学 | 2024-08-09 | — | — | CN | claimed |
| CN-115874199-B | In D2Functionalized deuterated olefin compound with O as deuterium source, and preparation method and application thereof | 天津大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117964614-A | 2,4,6 Substituted quinoline derivative and application thereof | 三峡大学 | 2024-05-03 | — | — | CN | claimed |
| CN-113845481-B | Synthesis method of 4, 4-dimethyl-4, 5-dihydropyridazin-3-one | 泉州师范学院 | 2023-05-30 | — | — | CN | claimed |
| CN-115874199-A | With D 2 Functional deuterated olefin compound with O as deuterium source and preparation method and application thereof | 天津大学 | 2023-03-31 | — | — | CN | claimed |
| CN-113845481-A | Synthesis method of 4, 4-dimethyl-4, 5-dihydropyridazin-3-one | 泉州师范学院 | 2021-12-28 | — | — | CN | claimed |
| CN-112391645-B | Synthesis method for preparing alpha, alpha-dibromo-ketone by electrochemically oxidizing alkyne and bromide | 武汉大学 | 2021-09-14 | — | — | CN | claimed |
| CN-112391645-A | Synthesis method for preparing alpha, alpha-dibromo-ketone by electrochemically oxidizing alkyne and bromide | 武汉大学 | 2021-02-23 | — | — | CN | claimed |
| CN-118580134-A | Preparation method of 1, 3-eneyne GEM isomer | 安徽大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-118459508-A | Iridium complex for inducing Mutp to degrade and preparation method and application thereof | 南京师范大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-115874199-B | In D2Functionalized deuterated olefin compound with O as deuterium source, and preparation method and application thereof | 天津大学 | 2024-06-04 | — | — | CN | disclosed |
| US-20230174965-A1 | METHODS AND PRODUCTS | UNIV BIRMINGHAM (GB) | 2023-06-08 | — | — | US | disclosed |
| CN-113845481-B | Synthesis method of 4, 4-dimethyl-4, 5-dihydropyridazin-3-one | 泉州师范学院 | 2023-05-30 | — | — | CN | disclosed |
| CN-115874199-A | With D 2 Functional deuterated olefin compound with O as deuterium source and preparation method and application thereof | 天津大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-101001842-A | Amido compounds and their use as pharmaceuticals | INCYTE CORP (US) | 2007-07-18 | — | — | CN | disclosed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| US-20050282858-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-22 | — | — | US | disclosed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |
| EP-1537135-A2 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022573-A2 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282858-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | LOXL2 3172/4885CYP2A6 283/4885KMT2A 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.