Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920535 | 0.94 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3AOC3KDM4E | |
| SCHEMBL24920536 | 0.81 | ACHE (0.48) | AOC3KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL24921023 | 0.80 | AOC3 (0.44) | AOC3KDM4EKMT2AACHE | |
| SCHEMBL24921040 | 0.80 | AOC3 (0.44) | AOC3MEN1KMT2AACHEHTT | |
| SCHEMBL24920520 | 0.79 | MAPT (0.46) | AOC3MEN1HPGDKMT2AACHE | |
| SCHEMBL15740824 | 0.77 | CYP11B1 (0.45) | CYP11B1CYP11B2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24920538 | 0.77 | DYRK1A (0.44) | LRRK2ALDH1A1L3MBTL1HTT | |
| SCHEMBL24920548 | 0.75 | ACHE (0.48) | AOC3MEN1ALDH1A1KMT2AACHE | |
| SCHEMBL24920567 | 0.75 | DYRK1A (0.38) | LRRK2AOC3ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL24920523 | 0.74 | ADRB1 (0.51) | AOC3KDM4EALDH1A1HPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |