Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9933093 | 0.75 | PDE10A (0.45) | ALDH1A1PDE10AKDM4EMAPK1GAA | |
| SCHEMBL8648652 | 0.75 | PDE10A (0.45) | ALDH1A1PDE10AKDM4EMAPK1GAA | |
| SCHEMBL5188673 | 0.75 | PDE10A (0.45) | ALDH1A1PDE10AKDM4EMAPK1GAA | |
| SCHEMBL362643 | 0.75 | PDE10A (0.45) | ALDH1A1PDE10AKDM4EMAPK1HPGD | |
| SCHEMBL5634310 | 0.75 | PDE10A (0.45) | ALDH1A1PDE10AKDM4EMAPK1GAA | |
| SCHEMBL13934564 | 0.75 | PDE10A (0.41) | ALDH1A1PDE10AKDM4EMAPK1GAA | |
| SCHEMBL12603986 | 0.75 | ALDH1A1 (0.42) | ALDH1A1PDE10AKDM4EMAPK1HPGD | |
| SCHEMBL22755250 | 0.75 | PDE10A (0.41) | ALDH1A1PDE10AKDM4EMAPK1HPGD | |
| Hydrochloric Acid SCHEMBL31728514 | 0.73 | PDE10A (0.40) | ALDH1A1PDE10AKDM4EMAPK1GAA | |
| SCHEMBL3457142 | 0.72 | PDE10A (0.39) | ALDH1A1PDE10AKDM4EMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080100-B1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2022-11-30 | — | — | EP | disclosed |
| EP-3287499-B1 | A METALLIC NANOPARTICLE DISPERSION | AGFA GEVAERT NV (BE) | 2021-04-07 | — | — | EP | disclosed |
| EP-3677583-A1 | NITROGENOUS HETEROCYCLIC COMPOUND, PREPARATION METHOD, INTERMEDIATE, COMPOSITION, AND APPLICATION | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2020-07-08 | — | — | EP | disclosed |
| CN-109642101-A | Metal nanoparticle dispersion | 爱克发-格法特公司 | 2019-04-16 | — | — | CN | disclosed |
| WO-2019042409-A1 | NITROGENOUS HETEROCYCLIC COMPOUND, PREPARATION METHOD, INTERMEDIATE, COMPOSITION, AND APPLICATION | 上海医药集团股份有限公司 | 2019-03-07 | — | — | WO | disclosed |
| US-20180200253-A1 | Heteroaromatic Compounds and their Use as Dopamine D1 Ligands | PFIZER INC. (US) | 2018-07-19 | — | — | US | disclosed |
| US-20170165270-A1 | Heteroaromatic Compounds and their Use as Dopamine D1 Ligands | PFIZER INC. (US) | 2017-06-15 | — | — | US | disclosed |
| US-9617275-B2 | Heteroaromatic compounds and their use as dopamine D1 ligands | PFIZER INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160304516-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | Quanticel Pharmaceuticals, Inc. | 2016-10-20 | — | — | US | disclosed |
| US-9430113-B2 | Electrically-conductive article with improved bus region | EASTMAN KODAK COMPANY (US) | 2016-08-30 | — | — | US | disclosed |
| EP-2009004-A1 | NOVEL PIPERAZINE COMPOUND, AND USE THEREOF AS HCV POLYMERASE INHIBITOR | Japan Tobacco, Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-20080081818-A1 | therapeutic agent for hepatitis C; R)-4-(4-trifluoromethyl-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 3-(4-isopropyl-benzylamide) 1-pyridin-4-ylamide; enzyme inhibitors | JAPAN TOBACCO INC. (JP) | 2008-04-03 | — | — | US | disclosed |
| US-20080081818-A1 | therapeutic agent for hepatitis C; R)-4-(4-trifluoromethyl-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 3-(4-isopropyl-benzylamide) 1-pyridin-4-ylamide; enzyme inhibitors | JAPAN TOBACCO INC. (JP) | 2008-04-03 | — | — | US | disclosed |
| WO-2005001568-A1 | PHOTOGRAPHIC ELEMENTS CONTAINING A DE-AGGREGATING COMPOUND, DYE-FORMING COUPLER, STABILIZER AND SOLVENT | EASTMAN KODAK COMPANY (US) | 2005-01-06 | — | — | WO | disclosed |
| US-5900357-A | SUPPORT COVERED ON AT LEAST ONE FACE WITH A LAYER OF SILVER HALIDE EMULSION WHICH CONTAINS AN EFFICIENT AMOUNT OF AT LEAST ONE FREE SPECTRAL SENSITIZING DYE. | EASTMAN KODAK COMPANY (US) | 1999-05-04 | — | — | US | disclosed |
| EP-0541067-A1 | Heat-developable photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |
| EP-0541104-A1 | Silver halide photographic emulsion and light-sensitive silver halide photographic material making use of the same | KONICA CORPORATION (JP) | 1993-05-12 | — | — | EP | disclosed |
| EP-0447534-A1 | COLOR PHOTOGRAPHIC RECORDING MATERIAL. | EASTMAN KODAK CO (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0128594-B1 | PHOTOGRAPHIC ELEMENTS FOR SILVER SALT DIFFUSION TRANSFER PROCESS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-07 | — | — | EP | disclosed |
| EP-0064861-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1987-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081818-A1 | therapeutic agent for hepatitis C; R)-4-(4-trifluoromethyl-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 3-(4-isopropyl-benzylamide) 1-pyridin-4-ylamide; enzyme inhibitors | HAVCR2, AADAC, DNPEP | ALDH1A1 96/4885PDE10A 4089/4885KDM4E 502/4885 |
| US-20180200253-A1 | Heteroaromatic Compounds and their Use as Dopamine D1 Ligands | COMT, DRD2, NR3C1 | ALDH1A1 2144/4885PDE10A 2689/4885KDM4E 3804/4885 |
| US-20170165270-A1 | Heteroaromatic Compounds and their Use as Dopamine D1 Ligands | ARRB1, DRD3, ADRB1 | ALDH1A1 3584/4885PDE10A 1805/4885KDM4E 4598/4885 |
| US-20160304516-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | KDM1B, KDM1A, KDM3A | ALDH1A1 235/4885PDE10A 2944/4885KDM4E 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.