Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 3/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
| ▸ | KIT | P10721 | 3/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934282 | 0.86 | ABL1 (0.37) | DDR2MAPK14ABL1KIT | |
| SCHEMBL24934276 | 0.78 | ABCB11 (0.35) | — | |
| SCHEMBL24934323 | 0.76 | RORC (0.37) | DDR2SRCMAPK9MAPK14RORC | |
| SCHEMBL24934256 | 0.75 | PSEN1 (0.36) | SRCMAPK9MAPK14RORC | |
| SCHEMBL24934295 | 0.73 | ABCG2 (0.38) | RORC | |
| SCHEMBL24934259 | 0.72 | ABCG2 (0.41) | DDR2RORCABL1KITDDR1 | |
| SCHEMBL30163209 | 0.69 | ROCK2 (0.48) | — | |
| SCHEMBL22890314 | 0.68 | — | — | |
| SCHEMBL24934233 | 0.66 | SCN9A (0.41) | MAPK9MAPK14RORC | |
| SCHEMBL4784150 | 0.64 | RORC (0.51) | MAPK14RORCABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |