Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897000 | 0.85 | LMNA (0.55) | LMNANAAAEPHX1TSHR | |
| SCHEMBL10087932 | 0.83 | LMNA (0.52) | LMNANAAAEPHX1TSHR | |
| SCHEMBL1469175 | 0.80 | NAAA (0.52) | LMNACES2NAAAEPHX1MEN1 | |
| SCHEMBL452059 | 0.77 | ALDH1A1 (0.52) | LMNANAAAEPHX1MAPTTSHR | |
| SCHEMBL1469943 | 0.77 | ALDH1A1 (0.50) | LMNACES2NAAAEPHX1TSHR | |
| SCHEMBL1469778 | 0.76 | ALDH1A1 (0.45) | CES2PLA2G2CEPHX1MAPTTSHR | |
| SCHEMBL7175331 | 0.76 | CES2 (0.59) | CES2PLA2G2CNAAAEPHX1MEN1 | |
| SCHEMBL895946 | 0.76 | CES2 (0.59) | CES2PLA2G2CNAAAEPHX1MEN1 | |
| SCHEMBL10937869 | 0.76 | USP2 (0.51) | LMNACES2PLA2G2CHTTMAPT | |
| SCHEMBL5550645 | 0.75 | LMNA (0.52) | LMNACES2PLA2G2CNAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230028516-A1 | PRODRUGS OF ITACONATE AND METHYL ITACONATE | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR V.V.I. (CZ) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028516-A1 | PRODRUGS OF ITACONATE AND METHYL ITACONATE | HADHA, IMPDH1, CYP27A1 | LMNA 2751/4885CES2 1078/4885PLA2G2C 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.