SCHEMBL24944652

SCHEMBL24944652

COc1cccc(C(=O)OC2(c3ccccc3)CCNCC2)c1C

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.42
OPRM1 P35372 1/20 0.41
KCNA3 P22001 2/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26413478 0.90 SIGMAR1 (0.46) SIGMAR1OPRM1KCNA3MEN1KMT2A
SCHEMBL24944277 0.88 KDM4E (0.42) OPRM1ALDH1A1
SCHEMBL24944092 0.88 KMT2A (0.49) SIGMAR1OPRM1MEN1KMT2AALDH1A1
SCHEMBL24944222 0.88 SIGMAR1 (0.42) SIGMAR1OPRM1KCNA3MEN1KMT2A
SCHEMBL24944859 0.86 OPRM1 (0.44) OPRM1MEN1KMT2A
SCHEMBL24944281 0.85 KMT2A (0.43) SIGMAR1OPRM1MEN1KMT2AALDH1A1
SCHEMBL24944862 0.85 SIGMAR1 (0.46) SIGMAR1OPRM1MEN1KMT2AALDH1A1
SCHEMBL26478756 0.84 OPRM1 (0.45) OPRM1
SCHEMBL26413498 0.84 OPRM1 (0.42) OPRM1MEN1KMT2A
SCHEMBL26413558 0.84 SMN1; SMN2 (0.41) SIGMAR1OPRM1KCNA3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11644753-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-09 US disclosed
US-11644753-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-09 US disclosed
US-20230131303-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230131303-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230021453-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11644753-B2 Resist composition and patterning process HNRNPU, NSUN2, HNRNPR SIGMAR1 327/4885OPRM1 775/4885KCNA3 1917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.