Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 7/20 | 0.50 |
| ▸ | ATF1 | P18846 | 5/20 | 0.50 |
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30202837 | 1.00 | NFKB1 (0.50) | NFKB1ATF1WDR5KDM4EALDH1A1 | |
| SCHEMBL24951630 | 0.89 | ALDH1A1 (0.50) | NFKB1ATF1KDM4EALDH1A1RAB9A | |
| SCHEMBL30202869 | 0.89 | ALDH1A1 (0.50) | NFKB1ATF1KDM4EALDH1A1RAB9A | |
| SCHEMBL24951146 | 0.86 | WDR5 (0.47) | NFKB1ATF1WDR5KDM4EALDH1A1 | |
| SCHEMBL30202783 | 0.86 | WDR5 (0.47) | NFKB1ATF1WDR5KDM4EALDH1A1 | |
| SCHEMBL24952216 | 0.84 | NFKB1 (0.50) | NFKB1ATF1KDM4EALDH1A1RAB9A | |
| SCHEMBL30202755 | 0.84 | NFKB1 (0.50) | NFKB1ATF1KDM4EALDH1A1RAB9A | |
| SCHEMBL30202682 | 0.77 | ALDH1A1 (0.46) | NFKB1ATF1WDR5KDM4EALDH1A1 | |
| SCHEMBL24951831 | 0.77 | ALDH1A1 (0.46) | NFKB1ATF1WDR5KDM4EALDH1A1 | |
| SCHEMBL26962799 | 0.74 | ALDH1A1 (0.76) | KDM4EALDH1A1CYP1A2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007009-A1 | PYRAZOLOPYRIMIDINES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-02-02 | — | — | WO | disclosed |