Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23561173 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRRAB9AKMT2AHSD11B1 | |
| SCHEMBL12089852 | 0.83 | HSD11B1 (0.41) | ALDH1A1RAB9AHSD11B1NPC1PIK3CD | |
| SCHEMBL14827254 | 0.82 | P4HTM (0.51) | ALDH1A1TSHRRAB9AKMT2ANPC1 | |
| SCHEMBL2677914 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRRAB9AKMT2ANPC1 | |
| SCHEMBL6651599 | 0.79 | PIK3CD (0.41) | RAB9AHSD11B1NPC1PIK3CDPIK3CA | |
| SCHEMBL24920071 | 0.78 | MAPK1 (0.54) | ALDH1A1TSHRRAB9AKMT2ANPC1 | |
| SCHEMBL9034066 | 0.78 | RAB9A (0.43) | ALDH1A1TSHRRAB9AKMT2ANPC1 | |
| SCHEMBL13144180 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRRAB9AKMT2ANPC1 | |
| SCHEMBL10272733 | 0.73 | MAPT (0.46) | ALDH1A1TSHRRAB9AKMT2ANPC1 | |
| SCHEMBL10258367 | 0.73 | HSP90AA1 (0.51) | ALDH1A1TSHRRAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | ALDH1A1 3556/4885TSHR 120/4885RAB9A 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.