Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24963420 | 0.84 | LMNA (0.41) | LMNAPROKR1POLBCES2CES1 | |
| SCHEMBL24964808 | 0.83 | CNR1 (0.37) | CCR9LMNAMAP4K4PROKR1POLB | |
| SCHEMBL24963385 | 0.81 | LMNA (0.43) | LMNAPOLBCES2CES1 | |
| SCHEMBL24964991 | 0.74 | CES2 (0.48) | LMNAPOLBCES2CES1 | |
| SCHEMBL24963392 | 0.74 | LRRK2 (0.49) | — | |
| SCHEMBL24964824 | 0.71 | LMNA (0.54) | LMNAIDO1POLBCES2CES1 | |
| SCHEMBL3554899 | 0.71 | PRSS1 (0.50) | UHRF1UBE2T | |
| SCHEMBL24964826 | 0.71 | LMNA (0.37) | LMNAMAP4K4IDO1POLB | |
| Hydrochloric Acid SCHEMBL20269638 | 0.70 | PRSS1 (0.48) | UHRF1UBE2T | |
| SCHEMBL21745897 | 0.69 | UHRF1 (0.48) | CCR9LMNAPROKR1UHRF1UBE2T |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004280-A1 | SELECTIVE PYRAZOLE LRRK2 INHIBITORS AND METHODS FOR USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-01-26 | — | — | WO | disclosed |