Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24963538 | 0.83 | CCR9 (0.38) | PROKR1CCR9LMNAMAP4K4POLB | |
| SCHEMBL24963385 | 0.78 | LMNA (0.43) | LMNAPOLB | |
| SCHEMBL24964967 | 0.76 | LRRK2 (0.52) | — | |
| SCHEMBL23539981 | 0.74 | PRSS1 (0.49) | PROKR1LOXLOXL2KCNK3KCNK9 | |
| SCHEMBL24963420 | 0.72 | LMNA (0.41) | PROKR1LMNAPOLBHPGD | |
| SCHEMBL24964991 | 0.71 | CES2 (0.48) | LMNAPOLB | |
| SCHEMBL24964824 | 0.69 | LMNA (0.54) | LMNAPLAUPOLB | |
| SCHEMBL445784 | 0.68 | NNMT (0.56) | PROKR1LOXLOXL2KCNK3KCNK9 | |
| SCHEMBL31318865 | 0.68 | CYP1A2 (0.54) | PROKR1LOXLOXL2LMNAKCNK3 | |
| SCHEMBL30281222 | 0.68 | NNMT (0.56) | PROKR1LOXLOXL2KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004280-A1 | SELECTIVE PYRAZOLE LRRK2 INHIBITORS AND METHODS FOR USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-01-26 | — | — | WO | disclosed |