SCHEMBL2496375

SCHEMBL2496375

CCCCCc1cnc(N=Nc2ncccn2)nc1N

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 12/20 0.43
TLR7 Q9NYK1 4/20 0.38
DHFR P00374 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9762812 0.82 TLR8 (0.43) TLR8TLR7DHFR
SCHEMBL4800682 0.77 L3MBTL1 (0.47)
Benzene SCHEMBL27894272 0.75 PKM (0.52) TLR8DHFR
SCHEMBL29352921 0.75 PKM (0.55) DHFR
SCHEMBL1554275 0.75 PKM (0.55) DHFR
SCHEMBL27768609 0.73 LMNA (0.54) TLR8
SCHEMBL16701417 0.73 PKM (0.54) DHFR
SCHEMBL16701413 0.73 PKM (0.54) DHFR
SCHEMBL9499492 0.73 PKM (0.54) DHFR
SCHEMBL609344 0.73 KCNH2 (0.51) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101528857-B Monoazo colorants for mass-colouring of polymers CIBA HOLDING INC 2013-07-17 CN disclosed
EP-2079805-B1 MONOAZO COLORANTS FOR MASS-COLOURING OF POLYMERS BASF SE (DE) 2012-08-01 EP disclosed
US-8013045-B2 Monoazo colorants for mass-colouring of polymers BASF SE Ludwigshafen (DE) 2011-09-06 US disclosed
US-20100305247-A1 MONOAZO COLORANTS FOR MASS-COLOURING OF POLYMERS CIBA CORP. 2010-12-02 US disclosed
US-20100168291-A1 MONOAZO COLORANTS FOR MASS-COLOURING OF POLYMERS CIBA CORPORATION (US) 2010-07-01 US disclosed
CN-101528857-A Monoazo colorants for mass-colouring of polymers CIBA HOLDING INC (CH) 2009-09-09 CN disclosed