SCHEMBL249662

SCHEMBL249662

FC(F)(F)Oc1ccc(OBOc2ccc(OC(F)(F)F)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
EPHX2 P34913 1/20 0.45
GPR3 P46089 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40
KIF11 P52732 1/20 0.39
PDE2A O00408 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
TRPV1 Q8NER1 2/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
KMT2A Q03164 2/20 0.38
MAOB P27338 1/20 0.38
AOC3 Q16853 1/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
BLM P54132 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1393571 0.93 EPHX2 (0.42) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL254957 0.84 MAPT (0.56) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL5541013 0.81 MAPT (0.47) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL177506 0.78 GPR3 (0.41) MAPTEPHX2GPR3KIF11ALDH1A1
SCHEMBL5534042 0.76 EPHX2 (0.44) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL28780452 0.76 EPHX2 (0.50) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL503302 0.75 SLC6A2 (0.37) MAPTKDM4EKIF11ALDH1A1KMT2A
SCHEMBL204711 0.75 CA1 (0.47) KIF11ALDH1A1TSHRMAOBAOC3
SCHEMBL255560 0.74 GPR3 (0.52) MAPTEPHX2GPR3L3MBTL1KDM4E
SCHEMBL13863723 0.74 MAPT (0.48) MAPTEPHX2GPR3L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353828-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-11-20 US disclosed
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-30 US disclosed
US-20250276509-A1 ORGANIC LIGHT EMITTING DIODE DISPLAY SAMSUNG DISPLAY CO LTD (KR) 2025-09-04 US disclosed
EP-3521366-B1 CURABLE MODIFIED PETROLEUM RESIN, AND PREPARATION METHOD AND USE THEREOF KOLON INC (KR) 2025-07-30 EP disclosed
US-12310224-B2 Organic light emitting diode display SAMSUNG DISPLAY CO., LTD. (KR) 2025-05-20 US disclosed
EP-4536639-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY Oregon Health & Science University (US) 2025-04-16 EP disclosed
US-20250074889-A1 Novel Aminobenzene Derivative Having Cancer Cell Growth Inhibitory Effect, and Preventive or Therapeutic Pharmaceutical Composition Containing Same as Active Ingredient DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-03-06 US disclosed
EP-4514777-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK Biopharmaceuticals Co., Ltd. (KR) 2025-03-05 EP disclosed
CN-114728980-B Pyrazole compounds 江苏先声药业有限公司 2025-02-07 CN disclosed
US-20240298513-A1 ORGANIC LIGHT EMITTING DIODE DISPLAY SAMSUNG DISPLAY CO., LTD. (KR) 2024-09-05 US disclosed
EP-1237887-A1 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS Applied Research Systems ARS Holding N.V. (AN) 2002-09-11 EP disclosed
US-20020115640-A1 Such as 4-(((6-chloro-2-(3-chlorophenyl)-3-pyridinyl) methoxy)(1-methyl-1H-imidazol-5-yl)methyl)benzonitrile; anticancer agents ABBOTT LABORATORIES 2002-08-22 US disclosed
EP-1232160-A1 SPIRO(2H-1-BENZOPYRAN-2,4'-PIPERIDINE)DERIVATES AS GLYCINE TRANSPORT INHIBITORS Akzo Nobel N.V. (NL) 2002-08-21 EP disclosed
EP-1224175-A2 BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2002-07-24 EP disclosed
WO-2001036423-A1 SPIRO(2H-1-BENZOPYRAN-2,4'-PIPERIDINE) DERIVATES AS GLYCINE TRANSPORT INHIBITORS AKZO NOBEL N.V. (NL) 2001-05-25 WO disclosed
WO-2001029012-A2 BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2001-04-26 WO disclosed
WO-2001029028-A1 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2001-04-26 WO disclosed
EP-1019410-A1 SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS MERCK SHARP & DOHME LTD. (GB) 2000-07-19 EP disclosed
US-6060469-A Spiro-piperidine derivatives and their use as tachykinin antagonists MERCK SHARP & DOHME LTD. (GB) 2000-05-09 US disclosed
WO-1997019084-A1 SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS MERCK SHARP & DOHME LIMITED (GB) 1997-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SCNN1B, SCN1B, SCN2B MAPT 3253/4885EPHX2 1625/4885GPR3 1597/4885
US-20250353828-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY EPX, TFEB, EPHX1 MAPT 3447/4885EPHX2 56/4885GPR3 2916/4885
US-20020115640-A1 Such as 4-(((6-chloro-2-(3-chlorophenyl)-3-pyridinyl) methoxy)(1-methyl-1H-imidazol-5-yl)methyl)benzonitrile; anticancer agents FNTB, FNTA, ACAT2 MAPT 2757/4885EPHX2 3179/4885GPR3 4656/4885
US-20250074889-A1 Novel Aminobenzene Derivative Having Cancer Cell Growth Inhibitory Effect, and Preventive or Therapeutic Pharmaceutical Composition Containing Same as Active Ingredient MKI67, CCNB1, ALDH7A1 MAPT 3752/4885EPHX2 3760/4885GPR3 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.