Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442433 | 0.75 | ALDH1A1 (0.65) | RXFP1PSMB8NPSR1ALDH1A1HPGD | |
| SCHEMBL21307598 | 0.75 | ALDH1A1 (0.50) | RXFP1PSMB8NPSR1ALDH1A1HPGD | |
| SCHEMBL104742 | 0.74 | LMNA (0.63) | RXFP1PSMB8NPSR1ALDH1A1HPGD | |
| SCHEMBL259052 | 0.74 | PSMB8 (1.00) | RXFP1PSMB8NPSR1ALDH1A1HPGD | |
| SCHEMBL21307492 | 0.74 | ALDH1A1 (0.62) | RXFP1PSMB8NPSR1ALDH1A1HPGD | |
| SCHEMBL29580191 | 0.71 | PSMB8 (0.55) | RXFP1PSMB8NPSR1POLBMEN1 | |
| SCHEMBL4706735 | 0.71 | PSMB8 (0.55) | RXFP1PSMB8NPSR1POLBMEN1 | |
| SCHEMBL17750892 | 0.70 | RXFP1 (0.49) | RXFP1PSMB8NPSR1ALDH1A1HPGD | |
| SCHEMBL5462899 | 0.69 | CDK4 (0.44) | RXFP1PSMB8NPSR1ALDH1A1HPGD | |
| SCHEMBL17749581 | 0.69 | MAPT (0.55) | NPSR1ALDH1A1SMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140163078-A1 | Mycobacterial Disease Detection, Treatment, and Drug Discovery | THE UAB RESEARCH FOUNDATION (US) | 2014-06-12 | — | — | US | claimed |
| US-20090068197-A1 | MYCOBACTERIAL DISEASE DETECTION, TREATMENT, AND DRUG DISCOVERY | THE UAB RESEARCH FOUNDATION (US) | 2009-03-12 | — | — | US | claimed |
| US-9822134-B2 | System for delivering therapeutic agents into living cells and cells nuclei | SABAG-RFA LTD. (IL) | 2017-11-21 | — | — | US | disclosed |
| WO-2017176981-A1 | SMALL MOLECULE REGULATORS OF STEROID RECEPTOR COACTIVATORS AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2017-10-12 | — | — | WO | disclosed |
| US-9556210-B2 | System for delivering therapeutic agents into living cells and cells nuclei | SABAG-RFA LTD. (IL) | 2017-01-31 | — | — | US | disclosed |
| US-20160176903-A1 | SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI | SABAG-RFA LTD. (IL) | 2016-06-23 | — | — | US | disclosed |
| US-20160039850-A1 | SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI | SABAG-RFA LTD. (IL) | 2016-02-11 | — | — | US | disclosed |
| US-9156865-B2 | System for delivering therapeutic agents into living cells and cells nuclei | DELIVERSIR LTD (IL) | 2015-10-13 | — | — | US | disclosed |
| US-8859490-B2 | Peptide nucleic acid monomers and oligomers | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-10-14 | — | — | US | disclosed |
| US-8759520-B2 | Compounds for treating cancer | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| US-8759520-B2 | Compounds for treating cancer | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070142388-A1 | Inhibitors of Akt activity | MERCK SHARP & DOHME CORP. | 2007-06-21 | — | — | US | disclosed |
| US-20070082906-A1 | Inhibitors of akt activity | MERCK SHARP & DOHME CORP. | 2007-04-12 | — | — | US | disclosed |
| WO-2007038172-A2 | GUANIDINIUM CARRIERS | NITTO DENKO CORPORATION (JP) | 2007-04-05 | — | — | WO | disclosed |
| US-20070078094-A1 | Guanidinium delivery carriers | NITTO DENKO CORPORATION (JP) | 2007-04-05 | — | — | US | disclosed |
| US-20070078078-A1 | Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues | NITTO DENKO CORPORATION (JP) | 2007-04-05 | — | — | US | disclosed |
| WO-2007038171-A2 | PEPTIDE NUCLEIC ACID BASED GUANIDINIUM COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2007-04-05 | — | — | WO | disclosed |
| US-20070072802-A1 | Peptide nucleic acid based guanidinium compounds | NITTO DENKO CORPORATION (JP) | 2007-03-29 | — | — | US | disclosed |
| US-20070043001-A1 | Inhibitors of akt activity | MERCK SHARP & DOHME CORP. | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163078-A1 | Mycobacterial Disease Detection, Treatment, and Drug Discovery | ANP32B, ANP32A, MRPL21 | RXFP1 2667/4885PSMB8 1809/4885NPSR1 4559/4885 |
| US-20160039850-A1 | SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI | NFATC1, KPNA2, KPNA6 | RXFP1 2534/4885PSMB8 3469/4885NPSR1 511/4885 |
| US-20070078094-A1 | Guanidinium delivery carriers | SLC2A9, SLC29A2, SLC2A4 | RXFP1 1046/4885PSMB8 4628/4885NPSR1 1176/4885 |
| US-20070043001-A1 | Inhibitors of akt activity | MTMR1, PIK3CA, PLK1 | RXFP1 4862/4885PSMB8 3320/4885NPSR1 4589/4885 |
| US-20090068197-A1 | MYCOBACTERIAL DISEASE DETECTION, TREATMENT, AND DRUG DISCOVERY | ANP32B, ANP32A, MRPL21 | RXFP1 2667/4885PSMB8 1809/4885NPSR1 4559/4885 |
| US-20070072802-A1 | Peptide nucleic acid based guanidinium compounds | SLC29A1, SLC29A2, SLC28A1 | RXFP1 992/4885PSMB8 3992/4885NPSR1 1176/4885 |
| US-20070082906-A1 | Inhibitors of akt activity | AKT2, AKT1, AKT3 | RXFP1 4855/4885PSMB8 2989/4885NPSR1 4385/4885 |
| US-20070078078-A1 | Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues | GLS, FABP2, GOLIM4 | RXFP1 3798/4885PSMB8 3444/4885NPSR1 3774/4885 |
| US-20160176903-A1 | SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI | NFATC1, KPNA2, KPNA6 | RXFP1 2534/4885PSMB8 3469/4885NPSR1 511/4885 |
| US-20070142388-A1 | Inhibitors of Akt activity | AKT2, AKT1, AKT3 | RXFP1 4871/4885PSMB8 2876/4885NPSR1 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.