Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of D-Glutamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP known ✓ | O00591 | 2/20 | 0.50 |
| ▸ | GABRD known ✓ | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 known ✓ | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 known ✓ | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 known ✓ | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 known ✓ | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 known ✓ | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 known ✓ | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.50 |
| ▸ | GABRA4 known ✓ | P48169 | 2/20 | 0.50 |
| ▸ | GABRE known ✓ | P78334 | 2/20 | 0.50 |
| ▸ | GABRA6 known ✓ | Q16445 | 2/20 | 0.50 |
| ▸ | GABRG1 known ✓ | Q8N1C3 | 2/20 | 0.50 |
| ▸ | GABRG3 known ✓ | Q99928 | 2/20 | 0.50 |
| ▸ | GABRQ known ✓ | Q9UN88 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | GRM8 | O00222 | 1/20 | 0.62 |
| ▸ | GRM6 | O15303 | 1/20 | 0.62 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL1899059 | 1.00 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL82751 | 1.00 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL4294624 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL10930916 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL1394398 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL11742429 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL2853216 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL11741892 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL10930108 | 0.96 | CYP1A2 (0.58) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL30787945 | 0.96 | CYP1A2 (0.58) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12582134-B2 | Non-dairy creamer and method of making the same | CARGILL, INCORPORATED (US) | 2026-03-24 | — | — | US | claimed |
| WO-2025097045-A1 | COLLOIDAL FOOD BASE COMPOSITIONS COMPRISING MYCELIAL BIOMASS | THE FYNDER GROUP, INC (US) | 2025-05-08 | — | — | WO | claimed |
| CN-119780054-A | Smart phone fluorescence data acquisition device and method for detecting potato dry rot by using same | 黑龙江省农业科学院经济作物研究所 | 2025-04-08 | — | — | CN | claimed |
| US-11992013-B2 | Feral hog toxicant | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-05-28 | — | — | US | claimed |
| CN-112125821-B | Aqueous solution containing N-long-chain acyl acidic amino acid and/or salt thereof and method for producing same | 味之素株式会社 | 2024-02-20 | — | — | CN | claimed |
| US-20230329239-A1 | Feral Hog Toxicant | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2023-10-19 | — | — | US | claimed |
| US-11716993-B2 | Feral hog toxicant | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2023-08-08 | — | — | US | claimed |
| US-20230049488-A1 | A NON-DAIRY CREAMER AND METHOD OF MAKING THE SAME | CARGILL, INCORPORATED (US) | 2023-02-16 | — | — | US | claimed |
| EP-4084621-A1 | A NON-DAIRY CREAMER AND METHOD OF MAKING THE SAME | Cargill, Incorporated (US) | 2022-11-09 | — | — | EP | claimed |
| US-20220132899-A1 | SEASONING COMPOSITION FOR REDUCED-SODIUM COMESTIBLES | AJINOMOTO CO., INC. (JP) | 2022-05-05 | — | — | US | claimed |
| EP-0420402-B1 | Use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs | INT FLAVORS & FRAGRANCES INC (US) | 1993-11-03 | — | — | EP | claimed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | claimed |
| EP-0420402-A2 | Use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1991-04-03 | — | — | EP | claimed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | claimed |
| EP-0110049-B1 | MIXED SEASONING | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1987-11-11 | — | — | EP | claimed |
| US-4514431-A | LACTIC ACID AND/OR THE POTASSIUM SALT, A POTASSIUM COMPOUND AND A POTASSIUM HALIDE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-04-30 | — | — | US | claimed |
| US-4472446-A | Uses of methyl(methylthioalkyl)-1,3-dithiolanes in augmenting or enhancing the aroma or taste of foodstuffs | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-09-18 | — | — | US | claimed |
| US-4471002-A | PHOSPHATES, POTASSIUM AND SODIUM COMPOUNDS, LACTIC ACID | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-09-11 | — | — | US | claimed |
| EP-0110049-A2 | Mixed seasoning | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-06-13 | — | — | EP | claimed |
| US-4216244-A | Low sodium salt seasoning | ALLEN ALFRED E JR | 1980-08-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12582134-B2 | Non-dairy creamer and method of making the same | CPT1B, FABP4, SCD | GABRP 3805/4885GABRD 3159/4885GABRA1 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.