Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MMP9 | P14780 | 6/20 | 0.48 |
| ▸ | MMP8 | P22894 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912705 | 0.87 | MMP13 (0.46) | ALDH1A1HPGDMAPTMMP13MMP2 | |
| SCHEMBL28555872 | 0.82 | MMP13 (0.47) | MMP13MMP2LEF1F11 | |
| SCHEMBL28555873 | 0.82 | MMP13 (0.47) | MMP13MMP2LEF1F11 | |
| SCHEMBL7833243 | 0.79 | LEF1 (0.55) | ALDH1A1HPGDMAPTGAAMMP13 | |
| SCHEMBL13676013 | 0.79 | MMP13 (0.62) | ALDH1A1HPGDMAPTGAAMMP13 | |
| SCHEMBL23486848 | 0.79 | PYGL (0.51) | MMP13F11 | |
| SCHEMBL23176635 | 0.77 | MAPT (0.61) | ALDH1A1HPGDMAPTGAARAB9A | |
| SCHEMBL23486667 | 0.77 | MMP13 (0.51) | ALDH1A1HPGDGAAMMP13MMP2 | |
| SCHEMBL15988495 | 0.75 | MAPT (0.58) | MAPTGAAMMP13MMP2MMP9 | |
| SCHEMBL28681216 | 0.74 | KLK7 (0.46) | MMP13MMP8LEF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027295-A1 | FXIA INHIBITORS AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027295-A1 | FXIA INHIBITORS AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | F11, TFPI, F7 | ALDH1A1 3516/4885HPGD 1092/4885MAPT 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.