Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.55 |
| ▸ | CDK9 | P50750 | 4/20 | 0.55 |
| ▸ | CDC7 | O00311 | 3/20 | 0.55 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.45 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27321112 | 0.84 | DRD2 (0.55) | PIM1CDK9CDC7DRD2DRD3 | |
| SCHEMBL24989033 | 0.80 | CHRNB2 (0.49) | PIM1CDK9CDC7MAPKAPK2DRD2 | |
| SCHEMBL24991124 | 0.78 | HTR1A (0.52) | PIM1CDK9CDC7PIM3ADRB2 | |
| SCHEMBL24989037 | 0.77 | KDM4E (0.58) | PIM1CDK9CDC7MAPKAPK2DRD2 | |
| SCHEMBL24990177 | 0.75 | DRD2 (0.69) | PIM1CDK9CDC7MAPKAPK2DRD2 | |
| SCHEMBL24990328 | 0.75 | ADRB2 (0.78) | PIM1PIM3ADRB2NCF1PLD1 | |
| SCHEMBL17116601 | 0.75 | MYC (0.65) | MYCCHEK1 | |
| SCHEMBL9792895 | 0.74 | MYC (0.62) | MYCCHEK1LRRK2 | |
| SCHEMBL15245011 | 0.74 | ADRB1 (0.68) | ADRB2NCF1PLD1TGFBR1HTR1A | |
| SCHEMBL31133396 | 0.74 | MYC (0.62) | MYCCHEK1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011596-A1 | AMIDE COMPOUND AND USE THEREOF | 中国药科大学 | 2023-02-09 | — | — | WO | disclosed |