Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 8/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 3/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26262796 | 0.83 | GABRA1 (0.36) | FEN1ALOX5APALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25003231 | 0.82 | CCR4 (0.37) | ALDH1A1CYP1A2CYP2C19CCR4SQOR | |
| SCHEMBL25003411 | 0.82 | ALOX5AP (0.38) | FEN1ALOX5APMAP4K1 | |
| SCHEMBL25003708 | 0.79 | ALOX5AP (0.35) | FEN1ALOX5APMAP4K1 | |
| SCHEMBL25003399 | 0.77 | ALDH1A1 (0.50) | FEN1ALOX5APALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25003239 | 0.75 | ABL1 (0.41) | FEN1ALOX5APALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25003722 | 0.74 | MAP4K1 (0.38) | FEN1ALOX5APMAP4K1 | |
| SCHEMBL25003725 | 0.72 | SQOR (0.40) | ALDH1A1CYP1A2CYP2C19SQORMAP4K1 | |
| SCHEMBL25004048 | 0.71 | MAP4K1 (0.39) | FEN1ALOX5APCYP1A2CYP2C19SQOR | |
| SCHEMBL25003184 | 0.71 | MAP4K1 (0.36) | FEN1ALOX5APCYP1A2CYP2C19SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295115-A1 | SUBSTITUTED ISOQUINOLINYLMETHYL AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2023-09-21 | — | — | US | disclosed |
| US-20230045421-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295115-A1 | SUBSTITUTED ISOQUINOLINYLMETHYL AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | HCCS, HAVCR2, HDGF | FEN1 2821/4885ALOX5AP 2603/4885ALDH1A1 3732/4885 |
| US-20230045421-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | HAVCR2, HMBS, AHCY | FEN1 975/4885ALOX5AP 3507/4885ALDH1A1 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.