SCHEMBL25006865

SCHEMBL25006865

CON(C)C(=O)C(F)(F)c1cccc(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.41
MLYCD O95822 1/20 0.38
PKM P14618 1/20 0.38
RAB9A P51151 1/20 0.38
OGG1 O15527 1/20 0.38
HSD11B1 P28845 1/20 0.37
GRM5 P41594 1/20 0.37
SCN5A Q14524 3/20 0.36
SCN9A Q15858 3/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
CCR6 P51684 1/20 0.36
KCNH2 Q12809 1/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30222838 1.00 RIPK1 (0.41) RIPK1MLYCDPKMRAB9AOGG1
SCHEMBL29433296 0.82 TSHR (0.46) MLYCDHSD11B1ALDH1A1CYP3A4CLK1
SCHEMBL22670274 0.82 TSHR (0.46) MLYCDHSD11B1ALDH1A1CYP3A4CLK1
SCHEMBL25007307 0.81 PTPN5 (0.48)
SCHEMBL30222787 0.81 PTPN5 (0.48)
SCHEMBL22658398 0.78 TP53 (0.50) PKMRAB9AALDH1A1GAAMAPT
SCHEMBL22670292 0.74 RXFP1 (0.52) PKMRAB9AALDH1A1GAAMAPT
SCHEMBL20591894 0.74 MEN1 (0.41) SCN5ASCN9AALDH1A1MAPTHTT
SCHEMBL9315537 0.74 KIF11 (0.44) RAB9ASCN5ASCN9AALDH1A1MAPT
SCHEMBL162341 0.73 MLYCD (0.46) RIPK1MLYCDRAB9AHSD11B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398757-A1 INHIBITORS FOR CORONAVIRUSES COCRYSTAL PHARMA, INC. 2024-12-05 US disclosed
EP-4380920-A1 INHIBITORS FOR CORONAVIRUSES Cocrystal Pharma, Inc. (US) 2024-06-12 EP disclosed
CN-118103351-A Coronavirus inhibitors 共晶制药公司 2024-05-28 CN disclosed
WO-2023014758-A1 INHIBITORS FOR CORONAVIRUSES COCRYSTAL PHARMA, INC. (US) 2023-02-09 WO disclosed
WO-2023014758-A1 INHIBITORS FOR CORONAVIRUSES COCRYSTAL PHARMA, INC. (US) 2023-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240398757-A1 INHIBITORS FOR CORONAVIRUSES ACE, ACE2, SARS1 RIPK1 3611/4885MLYCD 3947/4885PKM 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.