Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31689650 | 0.82 | EIF4A3 (0.47) | ITGB3ITGA2BALOX15 | |
| SCHEMBL21822456 | 0.82 | EIF4A3 (0.47) | ITGB3ITGA2BALOX15 | |
| SCHEMBL30180476 | 0.80 | DRD2 (0.51) | RETKDRSMYD3MLLT1DRD4 | |
| SCHEMBL28578333 | 0.80 | DRD2 (0.51) | RETKDRSMYD3MLLT1DRD4 | |
| SCHEMBL28578331 | 0.80 | DRD2 (0.51) | RETKDRSMYD3MLLT1DRD4 | |
| SCHEMBL21822433 | 0.78 | KDM4E (0.53) | RETKDR | |
| SCHEMBL21822374 | 0.78 | ALOX15 (0.53) | ALOX15 | |
| SCHEMBL8712416 | 0.77 | PLG (0.47) | RETKDRSMYD3ITGB3ITGA2B | |
| SCHEMBL8904038 | 0.77 | PLG (0.47) | RETKDRSMYD3ITGB3ITGA2B | |
| SCHEMBL32665962 | 0.73 | SMYD3 (0.60) | SMYD3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | RET 1443/4885KDR 1384/4885SMYD3 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.