Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25032061 | 0.84 | PDE5A (0.43) | PDE5ALRRK2RORCKMT2A | |
| SCHEMBL25032062 | 0.79 | RORC (0.40) | PTGS2PDE5ARORCPTGS1KMT2A | |
| SCHEMBL25032080 | 0.79 | RORC (0.40) | PTGS2PDE5ARORCPTGS1KMT2A | |
| SCHEMBL25032074 | 0.78 | KMT2A (0.40) | PTGS2TLR7PDE5ALRRK2KMT2A | |
| SCHEMBL25033637 | 0.76 | TLR7 (0.36) | CNR2TLR7PDE3BPDE3A | |
| SCHEMBL25033211 | 0.73 | TOP2B (0.48) | PTGS2PDE5ALRRK2KMT2A | |
| SCHEMBL25033617 | 0.73 | PTGS2 (0.42) | PTGS2LRRK2KMT2A | |
| SCHEMBL23144090 | 0.72 | CNR2 (0.40) | PTGS2CNR2PDK1PDK2PDK3 | |
| SCHEMBL25032067 | 0.70 | KMT2A (0.40) | PDE5ARORCKMT2A | |
| SCHEMBL23155765 | 0.70 | LRRK2 (0.46) | PTGS2CNR2PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |