Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | IL17A | Q16552 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25033211 | 0.89 | TOP2B (0.48) | PDE5AKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL25032080 | 0.86 | RORC (0.40) | PDE5AKMT2AMAPTALDH1A1TSHR | |
| SCHEMBL25032062 | 0.86 | RORC (0.40) | PDE5AKMT2AMAPTALDH1A1TSHR | |
| SCHEMBL25032067 | 0.84 | KMT2A (0.40) | PDE5AKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL25032058 | 0.84 | PTGS2 (0.40) | PDE5AKMT2ALRRK2RORC | |
| SCHEMBL25032074 | 0.84 | KMT2A (0.40) | PDE5AKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL25033642 | 0.81 | RORC (0.39) | PDE5AKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL25033302 | 0.81 | RORC (0.39) | PDE5AKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL25032057 | 0.80 | MAPT (0.38) | PDE5AKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL25033646 | 0.76 | MAPT (0.44) | MAPTALDH1A1LMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |